Institute of Liver and Biliary Sciences

 
Dr. Shiv Kumar Sarin
Designation
Senior Professor and Head, Department of Hepatology Director, Institute of Liver and Biliary Science (ILBS) Adjunct Prof. Molecular Medicine, Jawahar Lal Nehru Univ. New Delhi, Honorary Professor, Jawaharlal Nehru Center for Advanced Scientific Resea
 
Affiliation
Department of Gastroenterology, G.B. Pant Hospital, New Delhi - 110002. Affiliated to the University of Delhi.
Experience

Prof. (Dr.) S.K. Sarin, Director, Institute of Liver and Biliary Sciences,  is a clinician - a Gastroenterologist, Hepatologist,  a pioneer in clinical innovations, a gifted teacher, and a hybrid with great insights into basic and clinical research, a medical entrepreneur,  and an ambassador of enthusiastic learning. His contributions in reforms in medical education and health sciences are also noteworthy. 

At present he is working at the Institute of Liver and Biliary Sciences (ILBS), the first of its kind in Asia. ILBS is the first,  cost-effective and most comprehensive Liver Set-up in the region . The institute has a unique public perspective, most talented team of and administrators. The institute has already become a torch bearer of health care delivery and advanced learning.   It has been conferred the status of a Deemed-to be University by the GOI and UGC.  His main mission is to develop ILBS as the best possible institution of its kind in the world.

In his academic career spanning for nearly 30 years, he has immensely contributed internationally to the field of Liver diseases. His approach for Primary Prevention  of variceal bleeding by  band ligation,  has become  the standard of care worldwide.  Similarly, the  management  protocols on Gastric Varices; and the nomenclature bearing his name as ‘Sarin’s Classification of Gastric Varices” are universally followed.  He has more than 350 International publications to his credit, including  The New England Journal of Medicine, The Lancet, Annals of Internal Medicine, Gastroenterology and Hepatology. His deep interest in physiology has recently resulted in the development of a unique model of endotoxemia induced portal hypertension and liver disease. He has helped describe two new disease entities, portal biliopathy, and ‘Acute-on-Chronic Liver Failure”.He has edited eleven books on liver diseases, many of which are standard reference books and contributed more than 69 chapters in various medical text books. Dr. Sarin is the founding Chief Editor of a prestigious Journal, Hepatology International (Springer International).  He has served editorial assignments in most prestigious journals in the specialized fields.

 He is credited globally to give a huge number relevant and new protocols for the management of patients with hepatitis and cirrhosis of the liver and its complications. His recent contributions in the field of liver regeneration using growth factors has a great potential for patients with advanced liver disease and liver failure so as to provide options of transplant free survival.

 He has helped develop 17 major treatment guidelines, including spearheading five major Asian Pacific Treatment Guidelines in Liver diseases; which are widely quoted and practiced.

 He has immensely contributed to the field of hepatitis B, C and liver cancer. He is instrumental in changing the nomenclature of ‘Hepatitis B carrier’ to “Chronic HBV Infection”. The treatment options and pathogenesis of these diseases have been greatly advanced by his work. He is deeply involved in preventing and protecting new born babies from HBV transmission. His group showed that the mother baby transmission is the major route of transmission of hepatitis B in India. He also showed for the first time that the newborns born to these mothers are already chronically infected with HBV.  The treatment of hepatitis B and C, alcoholic liver disease and liver cancer are specially looked after by him.

 Along with the team of experts from Asia, he has been able to define a new disease entity, Acute on Chronic Liver Failure (ACLF). Since such patients have a high mortality, the need for protocol based treatment and special intensive care management has been established through his efforts. This has led to improved outcomes by their team.

 Prof. Sarin is credited with the help of the Governments of Delhi and Sikkim,  the launch of the Hepatitis B vaccination program in India. He undertook  to generate public awareness through mass contact and awareness program related to hepatitis in the country. Started organizing the “Yellow Ribbon  campaign” every year on December 4th since 1998. This proposal has been solely taken up by the GNCT of Delhi and for the past 15 years and the Govt of Delhi and all its hospitals and medical institutions organize this public awareness program. It has made a world of difference as now most schools of Delhi have also taken up this as part of their educational activity.

Prof. Sarin is also a academic clinician with research interests. He is credited with training nearly 90 post-doctoral students in the field of Gastroenterology and more than  two dozen students as guide for Doctor of Philosophy (Ph.D.) courses in basic sciences. For his outstanding contributions in the field of basic sciences, he has been appointed as an Adjunct Professor at the Special Center for Molecular Medicine at JNU and Jawaharlal Nehru Center for Advanced Research (JNCAR) Banglore.

Prof. Sarin was nominated to lead the Medical Council of India (MCI) as the Chairman of the Board of Governors, 2010-2011. He developed with other BOGs the ‘Vision 2015’ document for Medical Education in India. He introduced far reaching reforms in medical education and health sciences. 

Prof. Sarin has shown leadership roles in being the President of the Indian Society of Gastroenterology, Indin Association for the Study of the Liver, Asian Pacific Association of Liver (APASL), Vice President of International Association for Surgeons, Gastroenterologists and Oncologists, and now the Chairman Steering Committee of the APASL; responsible for major co-ordination of education and training in the Asian region.  Has immensely contributed to medical education in Liver diseases, and has set up the first APASL  School of Hepatology, in New Delhi India.

Prof. Sarin is a fellow of National Academy of Medical Sciences as well as he has been awarded fellowships from all the other major Science Academies of India [FNA, FASc, FNASc).  He is a  Member of External Advisory Board “Clinical Research Center at Severance Hospital, Yonossi University” Seoul, (Korea), Joint Steering Committee of Indo-German Science Centre for Infectious Diseases,  World Digestive Health Day (WDHD) Steering Committee,  External Advisory Board of the Institute of  Translation Hepatology at Beijing, (China), board member, Asian Pacific Digestive Week Federation (APDWF), Singapore.

Prof. Sarin, with his intense dedication, vision and work, is a role model for the country. He has been bestowed with Padma Bhushan by the Govt of India.

He is also the recipient of several other awards, the important ones being:  Shanti Swarup Bhatnagar Award, Third World Academy of Medical Sciences (TWAS)  International Prize, Om Prakash Bhasin Award for Health and Medical Sciences, Ranbaxy Medical Sciences Award in the field of Clinical Science, for basic clinical research work related to Liver disease, Dhanvantri Medical Award for outstanding Medical man, Amrut Mody Research Foundation Award for Outstanding Research in Gastroenterology, Hoechst Om Prakash Foundation Award, Fogarty Fulbright International Fellowship, Japanese Research Science Award, WHO fellowship at the University of Freiburg, Germany and at the Albert Einstein University, USA,  Dr. Dharamveer Datta Memorial Oration of ICMR, Rotary Award, Rashtriya Samman Puraskar of IEDRA, Lifetime Achievements Award of Delhi Govt., Knoll Oration Award of ISG, Netaji Oration of API, Mike Moshal Lecture of SAGES, South Africa, Dr. V.R. Khanolkar Oration of ICMR, Silver Jubilee Research Award of MCI, Dr. Y.S. Row Award of INSA, FICCI Award for Research and Development, Dr. Kunti Om Prakash Award of ICMR,  Bhagwan Mahaveer Award for  excellence in human endeavor in the field of Education & Medicine, DRC Gold Medal Oration, Malaysia Liver Foundation Award, Vashisht Chikitsa Ratan Award by DMA. He has recently been conferred with the Honorary Doctorate [D.Sc.]. He has also  conferred by the American Association Physicians of Indian origin the coveted prize of “The most distinguished physician from India.” He is one of the most sought teachers, invited speaker nationally and internationally, and has been awarded the “Gifted Teacher Award” by the Association of Physicians of India.

His humility and touch with the common man, integrity, far reaching contributions to the health and well being of his patients, have indeed left an indelible impact on the well-being of millions of people in the country.

ACADEMIC ACHIEVEMENT (2002-2003)

2002

  • Life Time Achievement State Award for Meritorious Services in the field of Medicine by the National Capital Territory Region of Delhi.
  • Nominated as the Chairman of the Research Council on Gastrointestinal Cancers by the Indian Council of Medical Research.
  • Elected as a Fellow of the American College of Gastroenterology.
  • Invited to Join the Editorial Board of J Hepatology.
  • Knoll Oration Award of the Indian Society of Gastroenterology.
  • Elected as President of Asian Pacific Association for the Study of Liver 2002-2004.

2003

  • Appointed as an Adjunct Professor in Molecular Medicine at the Special Centre for Molecular Medicine in Jawahar Lal Nehru University, New Delhi.
  • Awarded the 'Netaji Oration' for the year 2003, by the Association of Physicians of Indian, the highest Oration Award.
  • Nominated as a Fellow of the Indian College of Physicians
  • Awarded the prestigious Amrut Mody Unichem award for outstanding contributions in the field of Gastroenterology, by the Indian Council of Medical research.
  • Nominated as a Fellow of the Indian National Science Academy (INSA).
  • Awarded the Dr. J.C. Patel and Dr. B.C. Mehta best paper award for original work for the year 2002-2003 by the Journal of Association of Physicians of India.

 

ACADEMIC ACHIEVEMENT (2002-2003)


2004

  • Goyal Ankur, Kazim N Syed, Arora Naveen, Sakhuja Puja, Malhotra Veena and Sarin K Shiv. Association of TNF-� polymorphism with disease severity among HCV infected patients. J Med Virol 2004; 72(1):60-5.

2003

  • Rangari M, Gupta R, Jain M, Malhotra V and Sarin SK. Hepatic dysfunction in patients with extraheptic portal venous obstruction. Liver International 2003;23:434-439.
  • Solanki P, Chawla A, Garg R, Gupta R, Jain M, Sarin SK. Beneficial effects of terlipressin in heptorenal syndrome. A prospective, randomized placebo-controlled clinical trial. J Gastroenterol Hepatol 2003; 18:152-156.
  • Sarin SK, Jain AK, Lamba GS, Gupta R, ChowdharyA. Isolated gastric varices: Prevalence, clinical relevance and natural history. Digestive Srugery. 2003:20 (1):42-7
  • Thakur V, Kazim SN, Guptan RC, Malhotra V, Sarin SK. Molecualr Epidemiology and transmission of hepatitis B virus in close family contacts of HBV-related chronic liver disease patients J Med Virol 2003;70(4):520-8
  • Mendhekar DN, Srivastav PK, Sarin SK, Jiloha RC. A case report of olanzapine-induced fecal incontinence. J Clin Psychiatry. 2003 Mar; 64 (3): 339
  • Thakur V, Hashmi Z.A, Guptan R.C. Sakhuja P, Sarin SK. Absence of Hemochromatosis Associated Cys282Tyr HFE gene mutation and low frequency of Hemochromatosis Phenotype in non alcoholic chronic liver disease patients in India. J Gastroenterol Hepatol (in press)
  • Sarin SK, Goyal A, Kumar S, Guptan RC, Hashmi AZ, Sakhuja P and Malhotra V. A randomized trial of a 4 vs. 12 week daily interferon dose regimen combined with ribavirin in treatment of patients with chronic hepatitis C. HBPD Int 2003 (in press).

2002

  • Saigal S, Kapoor D, Tandon N, Thakur V, Guptan RC, Agarwal SR, Sarin SK. High seroprevalence and clinical significance of hepatitis B and C infection in hospitalized patients with alcoholic cirrhosis. J Assoc Physicians India 2002;50:1002-1006.
  • Sarin SK, Kapoor D. Non-cirrhotic portal fibrosis: current concepts and management. J Gastroenterol Heptol; 17:526-34
  • Kazim SN, Wakil SM, Khan LA, Hasnain SE, Sarin SK. Vertical transmission of hepatitis B virus despite maternal lamivudine therapy. Lancet. 2002 27;359(9316):1488-9
  • Gupta RC, Thakur V, Kazim SN, Sarin SK. Efficacy of granulocyte-merophage colony-stimulating factor or lamivudine combination with recombinant interferon in non-responders to interferon in hepatitis B virus-related chronice liver disease patients. J Gastroenterol Hepatol. 2002;17:765-771.
  • Ghosh S, Parvez MK, Banerjee K, Sarin SK, Hasnain SE, Baculovirus as Mammalian cell expression vector foe gene therapy: an emerging strategy. 2002;6:5-11
  • Guptan RC, Thakur V, Malhotra V, Sarin SK. Recombinant interferon therpay in Indian children with HBV related chronic liver disease. Indian Pediatr. 2002;39:462-7.
  • Sarin SK, Guptan RC, Malhotra S. Increased frequency of gallstones in cirrhotic and non-cirrhotic portal hypertension. J Assoc. Physicians India. 2002;50:518-22.
  • Guptan RC, Thakur, Safary A, Sarin SK. Immunogencity and reactogenicity of a combined paediatric dose 3 hepatitis A and hepatitis B (Twinrix) vaccine, compared to 4 adult dose Twinrix in healthy Indian children. Vaccine 2002;15:2102-6.
  • Rangari M, Sinha S, Kapoor D, Mohan JC, Sarin SK. Prevalence of Autonomic Dysfunction in Cirrhotic and Non-Cirrhotic Portal Hypertension. Am J Gastroenterol 2002:97(3):707-13.
  • Thakur V, Guptan RC, Kazim SN, Malhotra V, Sarin SK. Profile, spectrum and significance of HBV genotypes in chronic liver disease patients in the Indian subcontinent J Gastroenterol Hepatol 2002;17(2):165-170.
  • Wakil SM, Kazim SN, Khan LA, Raisuddin S, Parvez MK, Guptan RC, Thakur V, Hasnain SE, Sarin SK. Prevalence and profile of lamivudine induced mutations in the surface and polymerase genes of Hepatitis B Virus among Indian population. J Med Virol 2002;68:311-8.
  • Kathayat R, Pandey GK, Malhotra V, Omanwar S, Sharma BK, Sarin SK. A rabbit model of non-cirrhotic protal firosis (NCPF) with repeated immunosensitization by rabbit splenic extract. J Gatroenterol Hepatol 2002;17:1312-1316.
  • Sarin SK, Jain AK, Jain M, Gupta R. A randomized controlled trial of cyanoacrylate vs. alcohol injection in patients with isolated fundic varices. Am J Gastroenterol, 2002;97:1010-5.
  • Gupta RC, Thakur V, Malhotra V, Sarin SK. Clinical Implications of Viral Activity in Dual Infection with Hepatitis B and C in Chronic Liver Disease. J Assoc Physicians India 2002;50:651-655.
  • Sarin SK, Satapathy SK, Chauhan R. HBeAg negative chronic Hepatitis B. J Gastroenterol hepatol 2002;17:S311-S321.
  • Thakur V, Guptan RC, Malhotra V, Basri SF, Sarin SK. Prevalence of hepatitis B infection within family contacts of chronic liver disease patients: does HBeAg positivity really matter? JAPI 2002;50:1386-94.
  • V Thakur, RC Guptan, V Arankale*, SK Sarin. Low Specificity of the Third Generation Elisa for HCV Detection in Voluntary Blood Donors in India. EJIFCC 2002 (in Press).
  • Sarin SK, Agarwal SR. Extrahepatic protal vein obstruction. Semin Liver Dis. 2002;22(1):43-58.
  • Chandra R, Kapoor D, Agarwal SR, Malhota V, Sakhuja P, Sarin SK. Profile of Asymptomatic Chronic HBV Infection in India. Ind J Medical Research 2002;116:50-7.
  • Sarin SK, Satapathy SK. Endoscopic managment of oesophageal and gastric varices. Bombay Hospital Journal. 2002;44:515-533.
  • Sarin SK. Summary and recommendations of single theme conferences on hepatitis B and C: Indian Association for Study of the Liver (INASL). J Gastroenterol Hepatol 2002;17:1312-6.

2001

  • Chandra R, Kapoor D, Tharakan A, Chaudhary A, Sarin SK, Portal Biliopathy. J Gastroentrol Hepatol 2001;16(10:1144-8.
  • Parvez MK, Thakur V, Kazim SN, Guptan RC, Hasnain SE, Sarin SK. Bae-pair alterations in the epsilon-lower stem due toa novel double substitution in the precore gene of HBV-e negative variant were recovered by secondary mutation. Virus Genes. 2001;23(3):315-20.
  • Sarin SK, Thakur V, Guptan RC, Saigal S, Malhotra V, Thyagarajan SP, Das BC. Profile of Hepatocellular Carcinoma in India: An Insight Into The Possible Etiological Associations. J Gastro Hepatol. 2001;16:666-673.
  • Agarwal SR, Malhotra V, Sakhuja P, Sarin SK. Clinical, Biochemical And Histological Profile of Nonalcoholic Steatohepatitis. Indian J Gastro. 2001;20:183-6.
  • Thakur V, Guptan RC, Basir SF, Parvez K, Sarin SK. Enhanced immunogencity of Recombinant Hepatitis B Vaccine in Exposed Family contacts of Chronic Liver Disease patients. Scand J Infect Dis, 2001;33(8):618-21.
  • Sarin SK, Agarwal SR. Gastric varices and portal hypertensive gastropathy. Clin Liver Dis. 2001;5(3)727-67.
  • Bajaj JS, Bhattacharjee J, Sarin SK. Coagulation profile and platelet functions in patients with extrahepatic portal vein obstruction and non cirrhotic protal fibrosis and influence of hypersplenism. J Gastroenterol Hepatol. 2001;16:641-46.
  • Agarwal S, Sarin SK. Management protocols for hepatitis B. Indian J Gastroenterol, 2001,20 Suppl 1:C52-4.
  • Saigal S, Agarwal S, Nandeep HP, Sarin SK. Safety of ofloxacin based anti-tubercularregimen for the treatment of tuberculosis in patients with underlying chronic liver disease - A preliminary report". J Gastroenterol Hepatol 2001; 16(9):1028-32.
  • Gupta R, Jain M, Malhotra V, Sarin SK. Autoimmune hepatitis in Indian subcontinent: a 7 year experience. J Gastroenterol Hepatol 2001:16(10):1144-8.

2000

  • Sarin SK, Shahi HM, Jain M, Jain AK, Issar SK, Murthy NS. The natural history of Portal hypertensive gastropathy: influence of variceal eradication. Am J Gastroenterol 2000;95;2888-93.
  • Thakur V, Gyupta RC, Sarin SK. Prevalence of Hepatitis GBV-C/HGV infection in blood donors in India. JAPI 2000; 48:818-9.
  • Malhotra V, Sakhuja P, Gondal R, Sarin SK, Siddhu M, Dutt N. Histological comparison of chronic Hepatitis B and C in an Indian population. Trop Gastroenterol 2000;21:20-1.
  • Kapoor D, Saxena R, Sood B, Sarin SK. Blood transfusion practices in India: results of A national survey. Indian J Gastroenterol 2000;19:64-7.
  • Kapoor D, Sarin SK. What is safe blood JAPI 2000;48:335-42.
  • Tandon N, Thakur V, Guptan RC, Sarin SK. Beneficial influence of an indegenous low-iron diet on serum indicators of iron status in patients in India. Cancer 2000;88:1565-73.
  • Katiyar S, Dash BC, Thakur V, Guptan RC, Sarin SK, Das BC. P53 tumor supressor Gene mutationsin hepatocellular carcinoma patients in India. Cancer 2000;88:1565-73.
  • Kapoor D, Guptan RC, Wakil SM, Kazim SN, Kaul R, Agarwal SR, Raisuddin S, Hasain SE, Sarin SK. Beneficial effects of lamivudine in Hepatitis B virus related decompensated cirrhosis. J Hepatol, 2000;33:308-12.
  • Sarin SK, Singal AK. Hepatitis B Infection in India: Therapeutic Options and Prevention Strategies. Indian J Gastro 2000 Vol;19 suppl 3.
  • Sarin SK, Primignanai, Agarwal SR. Gastric varices. In: Portal Hypertension III. Proceedings of the Third Consensus Workshop on Definitions, Methodology and Therapeutic strategies. Edt. De Franchis R. Blackwell Science Publications, 2000;pp-76-94.
  • Sarin SK. What should we advise about adjunctive therapies, including herbal medicine, for Hepatitis C. J Gastroenterol Hepatol 2000;15:E164-171.
  • Primiganani M, Carpinelli L, Sarin SK, Kamath PS. Portal hypertensive gastropathy. In: Portal Hypertension III. Proceedings of the Third Consensus Workshop on Definitions, Mehtodology and Therapeutic strategies. Edt. de Franchs R. Blackwell Science Publications, 2000;pp65-76.
  • Das BC, Thakur V, Guptan RC, Sarin SK. P53 tumor suppressor gene mutations in HCC patients in India (Reply), Cancer 2000;88:2322-2323.

1999

  • Sarin SK, Lamba GS, Kumar M, Mishra A, Murthy NS. A comparison of endoscopic variceal ligation and propranolol for primary pervention of variceal bleeding. New Engl J Medicine 1999;340:988-93.
  • Mishra A, Saigal S, Gupta R, Sarin SK. Acute pancreatitis associated with viral hepatitis: A Report of Six Cases with Review of Literature. Am J Gastroenterol 1999:94:2292-5.
  • Sarin SK, Sharma G, Banerjee S, Kathayat R, Malhotra V. Hepatic fibrogenesis using chronic arsenic ingestion: Studies in a murine model. Indian J Experimental Biol 1999;37:147-151.
  • Guptan RC, V Thakur, V Raina, SK Sarin. Alpha Interferon therapy in chronic hepatitis due to active dual infection with hepatitis B and C viruses. Journal of Gastroenterology and Hepatology. 1999;14:796-80-1.
  • Saxena R, Thakur V, Sood B, Guptan RC, Gururaja S, Sarin SK. Transfusion - associated hepatitis in a tertiary referral hospital in India. Vox Sang 1999;77:6-10.
  • Kapoor D, Thakur V, Sing NP, Sarin SK. GM-CSF Enhances the efficacy of hepatitis B virus vaccine in previously unvaccinated hemodialysis patients. J Viral Hepatitis. 1999;6:405-9.
  • Sarin SK. "Transfusion Associated Hepatitis": In the Technical Report Series on Thalassaemia (In Press).
  • Sarin SK. Hepatobiliary anatomy and physiology. In: Ed. Sainani GS. API text book of Medicine, Association of Physicians of India, Mumbai 1999;pp 555-57.
  • Sarin SK, Chronic hepatitis. In: Ed. Sainani GS. API text book of Medicine, Association of Physicians of Indian, Mumbai 1999;pp-555-57.
  • Sarin SK. Nutrition in liver disease. In: Ed. Sainani GS. API text book of Medicine, Association of Physicians of India, Mumbai 1999;pp 555-57.
  • Sarin SK, Gupta R. Endoscopic ligation plus sclerotherapy: Two plus two make only three Gastrointest endosc 1999;50:988-93.

1998

  • Sehgal S, Malhotra V, Sarin SK. A case of hepatocellular carcinoma associated with troublesome hypoglycemia: management by cytoreduction using percutaneous ethanol injection. Am J Gastroenterol 1998;93:1380-1.
  • Chaudhary A, Dhar P, Sarin SK, et al. Bile duct obstruction due to portal biliopathy in extrahepatic protal hypertension: surgical management. Br. J Surg 1998;85:326-329.
  • Sarin SK. Transfusion associated hepatitis: summary, recommendations and issue INASL. In: Sarin SK, Hess G, eds Transfusion Associated Hepatitis, CBS Publications, New Delhi 1998, pp 479-484.
  • Guptan RC, Thakur V, Sarin SK. Hepatitis B virus mutant: Indian experience In : Sarin SK, Hess G. eds. Transfusion Associated Hepatitis, CBS Publications, New Delhi 1998, pp 39-48.
  • Sarin SK, Saxena R, Sundaram KR. Transfusion Assoicated Hepatitis: Risks and estimates in Indian population In: Sarin SK, Hess G eds Transfusion Assoicated Hepatitis, CBS Publications, New Delhi 1998, pp 212-220.
  • Guptan RC, Thakur V, Malhotra V, Sarin SK. Low dose recombinant interferon therapy in anti HBe positive chronic hepatitis B in Asian Indians. J Gastroenterol Hepatol 1998;13:675-9.
  • Thakur V, Guptan RC, Motwani J, Chopra K, Sarin SK. High frequency of hepatitis B and C virus dual infection in the lassemic children in India. JAPI 1998;46:856-859.
  • Shahi M, Sarin SK. Prevention of first variceal bleed: an appraisal of current therapies. Am J Gastroenterol 1998:93:2348-58.
  • Motwani J, Chopra K, Sarin SK. High-frequency of hepatitis B and C virus dual infection in Thalassemic children in Indian. JAPI 1998;46:856.
  • Jain R, Malhotra V, Kumar N, Sarin SK. Nuclear organizer regions in cirrhosis and hepatocellular carcinoma. Trop Gastroenterol 1998;19:100-1.
  • Sarin SK. Idiopathic portal hypertension. Digestion 1998;59:420-3.

1997

  • Sarin SK, Govil A, Jain AK, Guptan RC, Issar SK, Jain M, Murthy NS. Prospective randomized trial of endoscopic sclerotherapy versus variceal band ligation for esophageal varices: influence on gastropathy, gastric varices and avriceal recurrence. J Hepatology 1997:26:826-832.
  • Sarin SK, Dhingra N, Bansal A, Malhotra S, Guptan RC. Dietary and nutritional abnormalities in alcoholic liver disease: a comparison with chronic alcoholics wihouth liver disease. Am J Gastoenterol 1997; 92; 777-83.
  • Sarin SK, Long-term follow-up of gastric variceal sclerotherapy: An 11 year experience. Gstrointest Endosc 1997; 46:8-14.
  • Misra A, Sarin SK. Transmission of Hepatitis B: From Health Care workers to Patients. JAPI, 1997, Vol 45:392-95.
  • Lamba GS, Sarin SK. Subacute hepatic failure, Post Graduate Medicine 1997, 11: pp 295-302.
  • Aggarwal SR, Sarin SK. Non-cirrhotic portal hypertension. Medicine Update 1997; pp 390-98 API Text Book of Medicine, Ed. Das A.K. Pune Tech. India Ltd. 1997.
  • Sarin SK, Kumar M. Management of refractory ascites. Post graduate Med 1995; pp 99-108. Ed. Pathak Lekha CME Book.
  • Kapoor D, Sarin SK. Transfusion Associated Hepatitis: Indian Scenario. Indian Pediatrics 1997;34:1069-74.
  • Malhotra V, Gondal R, Tatke M, Sain SK. Fine needle aspiration cytologic appearance of inflammatory pseudotumor: a case report. Acta Cytol 1997;41:1325-8.

1996

  • Sarin SK, Guptan RC, Thakur V, Malhotra S, et al. Efficacy of low dose alpha interferon therapy in HBV-related chronic liver disease in Asia Indian patients: randomized controlled trial. J Hepatology 1996;24:391-96.
  • Sarin SK Familial prevalence of gallstone in first degree relatives of patients with gallstones. Hepatology 1996;23:1708.
  • Sarin SK Diagnostic issues "Portal Hypertension gastropathy and gastric varices. In Portal Hypertension. ed. Franchis de R. Blackwell Scientific Publication, Oxford 1996; pp 30-55.
  • Rawal KK, Jain M, Sarin SK. Hepatorenal syndrome. JAPI 1996;44:189-92.
  • Guptan RC, Thakur V, Sarin SK. Iron and liver; current concepts of the pathogensis and managment of Chronic liver disease. JAPI 1996; 44;3:198-202.
  • Sarin SK, Guptan RC, Banerjee K, Khandekar P. Low prevalence of hepatitis C viral infection in patients with chronic non-alcoholic liver disease in North India. JAI 1996;44:243-5.
  • Guptan RC, Thakur V, Sarin SK, Banerjee K, Khandekar P. Frequency and profile of precore and surface mutants in Asian Indian patients with chronic liver disease. Am J Gastroenterol 1996:91;1312-17.
  • Sarin SK, Guptan RC, Jain AK, Sundaram KR. A randomized controlled trial of endoscopic variceal band ligation for primary prophylaxis of variceal bleeding. Eur J Gastroenterol Hepatology 1996,8:337-42.
  • Sarin SK Etiology and profile of non-cirrhotic portal hypertension. In: proceeding of X Biennial Conference of the APASL, 1996.
  • Chaudhary A, Dhar P, Sachdev A, Kumar N, Viz JC, Sarin SK, Brool SL, Sharma SS, Choledochal cysts - differences in children and adults. Br J Surg 1996;83:186-88.

1995

  • Sarin SK, Negi S, Dewan R, Shailaja S, Saraya A. High familial incidence of gallstones inthe first degress relatives of gall stone patients. Hepatology 1995;22:138-141.
  • Ganguly S, Sarin SK, Bhatia V, Lahoti D. The prevalence and spectrum of colonic lesions in patients with cirrhosis and non-cirrhotic portal hypertension. Hepatology 1995;22:138-141.
  • Sarin SK, Saraya A. Effects of intravenous nitroglyserin and introglycerin and metoclopramide on intravariceal pressure - a double blind randomized study. Am J Gastroentrerol 1995;90:48-53.
  • Guptan RC, Sarin SK. Interferon therapy in chronic viral hepatitis. JAPI 1995; supply 3;44-51.
  • Bhatia V, Jain AK, Sarin SK. Choledocholothiasis associated with portal biliopathy in patients with extrahepatic portal vein obstruction - management with sphincterotomy. Gastrointest Endosc 1995;42:178-81.
  • Chawla A, Dewan R, Sarin SK. The frequency and influence of gall-bladder varices on gall bladder function in patients with portal Hypertension. Am J Gastroenterol 1995;90:2010-4.
  • Sarin SK, Gulati P. Drug related hepatic injuries. J Assoc. Physicians India 1995;42:689-93.

1994

  • Sarin SK, Sreenivas DV, Saraya A, Mehta S, Lahoti D, Malhotra V. Improved survival with percutaneous ethanol injecton (PEI) in patients with large hepatocellular carcinoma. Eur J Gastro Hepatol 1994;
  • Sarin SK. Hepatic Tumors. Med Intern Dec 1994.
  • Sarin SK, Non-cirrhotic portal hypertension. In: Portal Hyptertension, Ede.: Bosch J, Groszmann R, Blackwell Scientific Publications, Oxford, 1994; pp26-53.
  • Jagdish K, Patwari AK, Sarin SK, Prakash C, Srivastava DK, Anand VK. Hepatic manifestations in typhoid fever. Ind pediatr 994;31:807-11.
  • Bhatia V, Sarin SK. Visceral larva maigrans: evolution of the lesion, diagnosis and the role of albendazole therapy. Am J gastroenterol 1994;89:624-7.f.

1993

  • Sarin SK, Bhatia V. To ligate or sclerose - beginning of a new era om ,amage,emt pf esphageal varcies. Hepatology 1993;17:746-8.
  • Saraya A, Sarin SK. Effects of intravenous nigroglycerin andmetoclopramide on intravariceal pressure: a double blind randomized study. am J Gastroenterology 1993;88:1850-3.
  • Sarin SK. Treatment of variceal bleeding in the 1990's. Indian J Gastroenterol 1993; 12:116-119.
  • Yadav S, Dutta AK, SArin SK. Do Umbilical vein catheterization and sepsis lead to portal vein thrombosis? Clinical and sonographic evaluation. J Ped Gastreenterol Nutrition 1993; 17:392-96.
  • Lahoti D, Sarin SK. Interferon in Chronic Hepatitis B. HJAPI 1993; 41:295-299.
  • Bhatia V, Sarin SK. Therapeutic guidelines for subacute hepatic failure 1993; 12;Suppl. 3:25-7.
  • Sarin SK, Mehta S. Sclerotherapy failure salvage by oesophageal transection HPB Surgery 1993; 7:182-4.

1992

  • Sarin SK, Sreenivas D, Lahoti D, Saraya A. Factors influencing development of portal hypertensive gastropathy: role of sclerotherapy, severity of liver disease, variceal pressure, etiology of portal hypertension and presence of gastric varice. Gastroenterology 1992; 102:994-9.
  • Sarin SK, Bansal A, Sessan S, Nigam A. Portal vein obstruction in children leads to growth retardation. Hepatology 1992; 15:229.
  • Sarin SK, Lahoti D, Saxena SP, Murthy NS, Makwanae UK. Prevalence classification and natural history of gastric varices: A long-term follow-up study in 568 portal hypertension patients. Hepatology 1992; 16:1343-1349.
  • Sarin SK. Long-term management of oesophageal varices. Drugs 1992; 44:56-69 (Suppl. 2).
  • Banerjee K, Sarin SK, Naik SR, Khandekar P. Polymerase chain reaction based diagnostic assay for identification of hepatitis B virus. Ind J Med Res 1992; 95:173-178.
  • Sarin SK, Lahoti D. Management of gastric varices. Balliere's Clin Gastroenterology 1992; 6:527-48.

1991

  • Sarin SK, Groszmann RJ, Mosca PG, et al. Propranolol ameliorates the develoment of portal-systemic shunding in a chronic murine schistosomiasis model of portal hypertension. J Clin Invest 1991;87:1032-36.
  • Sarin SK, Sabba C, Mosca P, Groszmann RJ. Portal hypertension and hyperdynamic circulation in chronic murine schistosomiasis. Hepatology 1991; 13:581-84.
  • Sood GK, Mahaptra JR, Khurana A, Chowdhry V, Sarin SK, Brood SL. Caroli disease: computer tomographic diagnosis. Gastrointest Radio 1991; 16:243-244.
  • Misra SP, Singh SK, Chari ST, Sarin SK, Anand BS. Pyoderma gangrenosum in ulcerative colitis. J Assoc Physc India 1991;39:570-1.
  • Misra SP, Sarin SK, Gulati PK, Singh AK, Broor SL. Splenoportovengography: safetyd success rate and hemodynamic changes and natural history of splenic hematoma. Ind J fastroenterol 1991;10:49-50.

1990

  • Sarin SK, Sabba C, Groszmann RJ. Splanchnic and systemic hemodynamics hemodynamics in mice using a radioactive microsphere technique Am J Physiol 1990;258:365-69.
  • Sarin SK. Sclerotherapy with alcohol - a double edged sword. Heptology 1990;11:325-27.
  • Singal AK, Sarin SK, Sood G, Broor SL. Ulcer following intravariceal sclerotherapy, correlation of symptoms and factors influencing healing. J Clin Gastroenterol 1990;12:250-4.
  • Sarin SK, Kumar A. Sclerosants for variceal sclerotherapy. Am J Gastroenterol 1990;85:641-9.
  • Sarin SK, Nayyar AK, Malhotra P, Sharma BK, Kumar R, Broor SL. Immunological profile with non-cirrhotic portal fibrosis. J Gastroenterol Hepatol 1990;5:554-9.
  • Nayyar AK, Sharma BK, Sarin SK, et al. Characterization of peripheral blood lymphocytes in patients with cirrhosis and controls. J Gastroenterol Hepatol 1990;5:554-9.
  • Mehandiratta MM, Sood GK, Sarin SK, et al. Comparative evaluation of visual, somatosensory and auditory evoked potentials in the detection of subclinical hepatic encephalopathy in patients with non-alcoholic cirrhosis. Am J Gastroenterol 1990;85:799-83.
  • Carlo S, Giovanna F, Sarin SK et al. Feasibility spectrum for doppler flowmetry of splanchnic vessels in normal and cirrhotic population. J Ultrasound Med 1990;9:705-10.
  • Sarin SK. Endoscopic sclerotherapy with alcohol; There is truth in wine. Indian J Gastroenterology 1990;9:84-7.
  • Sarin SK, Sood GK. Liver biopsy: technique and interpretation .Nat Med Jour 1990 (Sept.).
Qualification
M.B.B.S : M.B.,B.S Rajasthan University Jaipur, India (Bachelor of Medicine & Surgery) 1974
M.D. : M.D. Rajasthan University, Jaipur,India General Medicine and Therapeutics, 1978
D.M. : All India Institute of D.M. Gastroenterology,Medical Sciences, New Delhi 1981
Number of publications
360
Awards

1974
Graduated from Rajasthan University, Sawai Man Singh Medical College at Jaipur, securing Ist
Position in five medical colleges of the University of Rajasthan and bagged Seven gold medals

1974-1976
Topped Rajasthan University in both Ist and 2nd years of L.L.B. and was awarded
University medal and merit scholarship

Awarded the University of Rajasthan Outstanding Merit Scholarship for three
years during postgraduation

1985-1986

Searle Award for best research paper of the year, of the Indian Society of
Gastroenterology

1986
Invited as Senior Scientist by the Japanese Society for Promotion of Science
JSPS Chiba, Japan

1987
Elected to the Governing Council of Indian Society of Gastroenterology

1987
Awarded “Amrut Mody Research Foundation Award” for Outstanding Research in
Gastroenterology

1987
Received the “Hoechst Omprakash Memorial Award” of the Indian Society of
Gastroenterology, for the best research work in the year

1987
Nominated as the Secretary of the Indian Association for Study of the Liver
{INASL}

1987
Invited to join the Editorial Board of the Journal of Gastroenterology and
Hepatology

1988
Awarded the “Fogarty International Fellowship” by the National Institute of Health
and worked at the prestigious Hepatic Hemodynamic Laboratory at the Yale
University School of Medicine

1988
Nominated to the subcommittee of the International Association for Study of the
Liver {IASL} for developing countries.

1989
Received the “Dr. Dharamveer Datta Memorial Oration Award of the Indian Council
of Medical Research, for outstanding work in the field of Liver Diseases.

1990
Renominated as Secretary of the Indian Association for Study of the Liver (1990-93).

1991-92.
Awarded the “Olympus J. Mitra Award” for distinguished work in the field of
endoscopy ,

1994
“Unichem Lecturership in Gastroenterology” 1994, of Association of Physicians of
India

Awarded the “Dr. B.J. Vasa Memorial Oration” for the year 1994,
at Baroda Elected Vice-President of the Indian Association for Study of the Liver (INASL)

1995
Awarded the prestigious “Nahar Sanman Puruskar”, for outstanding contribution in the field of Medicine,
by Rajasthan Welfare Association, for the year 1995

“Rotary Award” for outstanding services in the field of Medicine, for the year 1995

1995
Awarded the “Shri Raghu Manth Rai Shroff Memorial Award” for outstanding
contribution in the field of Medicine, May 1995

1996
Awarded “Ranbaxy Research Foundation Award” in the field of Clinical Science,
for basic clinical research work related to Liver disease.

1996
Invited to join the Editorial Board of “Hepatitis World” and “Medicine Today”.

1996
Invited to be the Member of the Executive Council of the Asian Pacific Association for the
Study of the Liver (1996-1998)

1996
Received the “Shanti Swaroop Bhatnagar Prize”, in the field of Medical Science from the Central Scientific and Industrial Institute.

  • Elected as a “Fellow of the National Academy of Science”, Allahabad.
  • Selected as an Editor of “The Journal of Gastroenterology and Hepatology”
  • Elected the Vice-president of the Asian Pacific Association for Study of the Liver (APASL)

1997
Nominated to the Governing Council of Central Ayurvedic Research Institute,
Govt. of India

  • Elected as an Editor of “The Journal of Gastroenterology and Hepatology”
  • Elected the Vice-president of the Asian Pacific Association for Study of the Liver (APASL)

1999
Awarded the "Gifted Teacher" award, the highest award by the Association of Physicians of India.

Awarded the WHO fellowship for advanced studies, at the University of
Freiburg, Germany and at the Albert Einstein University,

USAAwarded the prestigious award of the Indian Society of Gastroenterology, “The Parke-Davis Gastroenterology Oration Award”

2000
Awarded the “Rashtriya Samman Puruskar” by the Indian Economic Development & Research
Association (IEDRA) in June, 2000.

Awarded the “Dr. R,M, Kasliwal Award for Outstanding Research in Medical Sciences”, by the
Prof. P.C.Dandiya Endowment Trust.

2001
Invited to join the Editorial Board of prestigious international journal, Journal of
Hepatology and the World Journal of Gastroenterology.

2002
Life Time Achievement State Award for Meritorious Services in the field of Medicine, by the
National Capital territory Region of Delhi.

  • Elected as a Fellow of the American College of Gastroenterology
  • Knoll Oration Award of the Indian Society of Gastroenterology.

2003
Appointed as an Adjunct Professor in Molecular Medicine at the Special Centre for Molecular Medicine in Jawahar Lal Nehru University, New Delhi

Awarded the 'Netaji Oration" for the Year 2003, by the Association of Physicians of India, the
highest Oration Award.

Fellow of the Indian College of Physicians from January 2003

Amrut Mody Unichem award for outstanding contributions in the field of Gastroenterology, by the Indian Council of Medical research

Fellow of the Indian National Science Academy (INSA)

Awarded the Dr J.C.Patel and Dr B.C.Mehta best paper award for original work for the year 2002-2003 by the Journal of Association of Physicians of India.

Mike Moshal Lecture, South African Gastroenterology Society (SAGES) at the SAGES Congress, Sandton 2003.

2004
Awarded with the prestigious award of the “The Third World Academy of Sciences (TWAS) in Medical Sciences”

Dr. V.R. Khanolkar Oration for the year 2003-2004 by National Academy of Medical Sciences (India)

2005
Fellow of the Indian Academy of Sciences

Fellow of the National Academy of Medical Sciences (India)

Silver Jubilee Research Award of the Medical Council of India (MCI) for outstanding Research Work.

Dr. Yellapragada SubbaRow Memorial Lecture (2005) by Indian National Science Academy

FICCI Awards 2004-05 R & D in Life Sciences including Agriculture and Bio-technology.

2006
Award of the Delhi Medical Association for outstanding contribution in the field of Gastroenterology

2006
Fellow of TWAS by the Academy of Sciences for the Developing world

2007
Awarded the Padma Bhushan, the 3rd highest civilian honour by the President of India.

2007
Invited to be Editor-in-Chief of Hepatology International, a global journal in the field of Hepatology

2007
Awarded the Drs. Kunti & Om Prakash Award (2004: Infectious Diseases) by the ICMR.

Shri Om Prakash Bhasin Award for Science and Technology for year 2007 in the field of Health
and Medical Sciences.

2008
Awarded for the Eleventh Mahaveer Awards of the Bhagwan Mahaveer Foundation for excellence in human endeavor in the field of Education & Medicine.

2008
Nominated as an Associated Editor in the journal Digestive and Liver Disease.

2009
Awarded the Dr. Yellapragada Subba Row Memorial Oration, by the Central University of Hyderabad

2010
Appointed as a Chairman, Board of Governors, Medical Council of India.

2011
Awarded DRC Gold Medal Oration 2010 from Diabetes Research Centre
Foundation, Chennai

2011
Awarded Dr. L R Sarin Memorial Oration for the year 2010 by the SMS Medical
College FOUR DECADE TRUST, Jaipur

2011
Awarded “The Most Distinguished Physician from India” by the American
Association of Physicians of Indian Origin, USA

2013

Awarded the “Master Teacher’’ award in recognition and appreciation for the outstanding contribution towards the Medical Education by the Indian College of Physicians on February 1, 2013
Awarded Lifetime achievement award in the field of Gastroenterology by ISGCON Bihar and Jharkhand Chapter, May , 2013
Awarded Malaysian Liver Foundation Lecture Award at the 10th Liver Update at Kuala Lumpur, Malaysia, June , 2013.

Awarded ‘Vashisht Chikitsa Ratan Award’ on Doctors Day for Distinguished Services and outstanding contribution to medical profession and the society by Delhi Medical Association

Awarded 2nd K B Grant Memorial Oration on occasion of World Hepatitis Day on July 28, 2013 at ,Pune

Awarded the most prestigious Medical award “Dhanvantari Award 2013” for outstanding Medical man by the Dhanvantari Medical Foundation, Mumbai on October 27, 2013

Awarded Life Time Achievement Award for dedicated work and contributions in developing the specialty of Hepato Biliary Sciences at 5th International Conference and Live Workshop on Bariatric Surgery (Laparofit 2013) at Bangalore on November 9, 2013

Awarded The Swami Rama Humanitarian Award 2013 for contributions in the field of Health care and Medical education benefiting humanity at large by the Himalayan Institute Hospital Trust, Dehradun on November 13, 2013.

Awarded “Dr. Phanidhar Memorial Lectue’’ at RAPICON 2013 at Railway Chapter of Association for Physicians of India on November 24, 2013, Mumbai

Awarded ISG-FP Antia Life Time Achievement Award 2013 in recognition of outstanding work in the field of Gastroenterology and Hepatology at 54 Annual Conference of the Indian Society of Gastroenterology at Ahmedabad on November 28, 2013

 

Editorial Review Assignments

  • Gastroenterology,
  • Hepatology,
  • Hepatology International (Editor-in-Chief)
  • J Hepatology (Editorial Board),
  • J Gastroenterology and Hepatology (Editorial Board),
  • J Clinical Gastroenterology,
  • Hepatogastroenterology (Editorial Borad)
  • World Journal of Gastroenterology (Editorial Board),
  • Digestive Diseases and Sciences,
  • Digestive and Liver Diseases (Associate Editor)
  • American J Gastroenterology,

Prestigeous Fellowships

  • American College of Gastroenterology
  • Indian Academy of Science
  • Indian National Science Academy
  • Indian College of Physicians
  • National Academy of Medical Sciences (India)
  • Third World Academy of Sciences (TWAS)

Memberships

  • International Association for Study of Liver {IASL}
  • American Association for Study of the Liver {AASLD}
  • American Gastroenterology Association {AGA}
  • Asian Pacific Association for Study the Liver {APASL}
  • Indian Association for Study of the Liver {INASL}
  • Indian Academy of Gastroenterology (IAG)
  • Association of Physicians of India (API)
  • International Association of Surgeons, Gastroenterologists and Oncologists (IASGO)

Representation in the Professional Bodies

Vice President- International Association of Surgeons, Gastroenterologists
and Oncologists (IASGO) 2006

  • Executive Council of The International Association for Surgeons and Gastroenterologist 2005
  • President of the Asian pacific Association for the Study of the Liver (APASL) -2002-2004
  • President of the Indian Association for the Study of the Liver (INASL) -2000-2002
  • Councilor International Association for the Study of the Liver (IASL) -2002-2004
  • Past President of the Indian Society of Gastroenterology -2000
Publications

2011

  • Sarin SK, Kumar M. A Vaccine for Hepatitis E: Has It Finally Arrived? Gastroenterology. 2011;140(4):1349- 52
  • Garg H, Sarin SK, Kumar M, Garg V, Sharma BC, Kumar A. Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure. Hepatology. 2011 Mar;53(3):774-80
  • Kumar R, Sundar S, Sharma P, Sarin SK. Conservative management of liver abscess complicated by hepatogastric fistula. Dig Liver Dis. 2011 Jun 3
  • Mittal VV, Sharma BC, Sharma P, Sarin SK. A randomized controlled trial comparing lactulose, probiotics, and L-ornithine L-aspartate in treatment of minimal hepatic encephalopathy. Eur J Gastroenterol Hepatol. 2011 Jun 3.
  • Sharma P, Singh S, Sharma BC, Kumar M, Garg H, Kumar A, Sarin SK. Propofol sedation during endoscopy in patients with cirrhosis, and utility of psychometric tests and critical flicker frequency in assessment of recovery from sedation. Endoscopy. 2011 May;43(5):400-5.
  • Liaw YF, Raptopoulou-Gigi M, Cheinquer H, Sarin SK, Tanwandee T, Leung N, Peng CY, Myers RP, Brown RS Jr, Jeffers L, Tsai N, Bialkowska J, Tang S, Beebe S, Cooney E. Efficacy and safety of entecavir versus adefovir in chronic hepatitis B patients with hepatic decompensation: A randomized open-label study. Hepatology. 2011 Jul;54(1):91-100.
  • Pande C, Sarin SK, Patra S, Bhutia K, Mishra SK, Pahuja S, Jain M, Srivastava S, Dar SB, Trivedi SS, Mukhopadhyay CK, Kumar A. Prevalence, risk factors and virological profile of chronic hepatitis b virus infection in pregnant women in India. J Med Virol. 2011 Jun;83(6):962-7.
  • Sarin SK, Kumar A, Angus PW, Baijal SS, Baik SK, Bayraktar Y, Chawla YK, Choudhuri G, Chung JW, de Franchis R, de Silva HJ, Garg H, Garg PK, Helmy A, Hou MC, Jafri W, Jia JD, Lau GK, Li CZ, Lui HF, Maruyama H, Pandey CM, Puri AS, Rerknimitr R, Sahni P, Saraya A, Sharma BC, Sharma P, Shiha G, Sollano JD, Wu J, Xu RY, Yachha SK, Zhang C; Asian Pacific Association for the Study of the Liver (APASL) Working Party on Portal Hypertension. Diagnosis and management of acute variceal bleeding: Asian Pacific Association for Study of the Liver recommendations. Hepatol Int. 2011 Jun;5(2):607-24.
  • Kumar M, Sharma P, Garg H, Kumar R, Bhatia V, Sarin SK. Transient Elastographic Evaluation In Adult Subjects Without Overt Liver Disease: Influence Of Alanine Aminotransferase Levels. J Gastroenterol Hepatol. 2011 Mar 28.
  • Trehanpati N, Sukriti S, Geffers R, Hissar S, Riese P, Toepfer T, Guzman CA, Sarin SK. Gene Expression Profiles of T Cells from Hepatitis E Virus Infected Patients in Acute and Resolving Phase. J Clin Immunol. 2011 Feb 3.
  • Tyagi P, Sharma P, Sharma BC, Puri AS, Kumar A, Sarin SK. Prevention of hepatorenal syndrome in patients with cirrhosis and ascites: a pilot randomized control trial between pentoxifylline and placebo. Eur J Gastroenterol Hepatol. 2011 Mar;23(3):210-7.
  • Sharma P, Singh S, Sarin SK. Hyponatremia in patients with acute variceal bleeding treated with terlipressin. Hepatology. 2011 Feb;53(2):714.
  • Bose S, Sakhuja P, Bezawada L, Agarwal AK, Kazim SN, Khan LA, Sarin SK, Ramakrishna G. Hepatocellular carcinoma with persistent hepatitis B virus infection shows unusual downregulation of Ras expression and differential response to Ras mediated signaling. J Gastroenterol Hepatol. 2011 Jan;26(1):135- 44.
  • Trehanpati N, Kotillil S, Hissar SS, Shrivastava S, Khanam A, Sukriti S, Mishra SK, Sarin SK. Circulating Tregs Correlate with Viral Load Reduction in Chronic HBV-Treated Patients with Tenofovir Disoproxil Fumarate. J Clin Immunol. 2011 Feb 9.
  • Franchis R and Baveno V faculty. Revising consensus in portal hypertension Report of the Baveno V Consensus Workshop on methodology of diagnosis and therapy in Portal Hypertension. J Hepatol. 2011 May;54(5):1082-3.
  • Sharma P, Agrawal A, Sharma BC, Sarin SK. Prophylaxis of hepatic encephalopathy in acute variceal bleed: A randomized controlled trial of lactulose versus no lactulose. J Gastroenterol Hepatol. 2011 Jun;26(6):996- 1003

    2010
  • Garg H, Sarin SK, Kumar M, Garg V, Sharma BC, Kumar A. Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure. Hepatology 2010, Dec 14
  • Sharma P, Sharma BC, Sarin SK. Critical flicker frequency for diagnosis and assessment of recovery from minimal hepatic encephalopathy in patients with cirrhosis. Hepatobiliary Pancreat Dis Int. 2010 Feb;9(1):27-32.
  • Bui-Nguyen TM, Pakala SB, Sirigiri RD, Xia W, Hung MC, Sarin SK, Kumar V, Slagle BL, Kumar R. NF-kappaB signaling mediates the induction of MTA1 by hepatitis B virus transactivator protein HBx. Oncogene. 2010 Feb 25;29(8):1179-89.
  • Sharma P, Kumar A, Jha S, Mishra SR, Sharma BC, Sarin SK. Hemodynamic response to propranolol in cirrhosis with arterial hypertension: a comparative analysis with normotensive cirrhotic patients. Aliment Pharmacol Ther. 2010 Jul;32(1):105-12.
  • Sharma P, Sharma BC, Sarin SK. Predictors of nonresponse to lactulose in patients with cirrhosis and hepatic encephalopathy. Eur J Gastroenterol Hepatol. 2010 May;22(5):526-31
  • Kumar A, Mishra SR, Sharma P, Sharma BC, Sarin SK. Clinical, laboratory, and hemodynamic parameters in portal hypertensive gastropathy: a study of 254 cirrhotics. J Clin Gastroenterol. 2010 Apr;44(4):294-300.
  • Sharma P, Sharma BC, Sarin SK. Prevalence of abnormal psychometric tests and critical flicker frequency after clinical recovery of overt hepatic encephalopathy. Neurol India. 2010 Mar-Apr;58(2):220-4.
  • Dhiman RK, Saraswat VA, Sharma BK, Sarin SK, Chawla YK, Butterworth R, Duseja A, Aggarwal R, Amarapurkar D, Sharma P, Madan K, Shah S, Seth AK, Gupta RK, Koshy A, Rai RR, Dilawari JB, Mishra SP, Acharya SK. Minimal hepatic encephalopathy: Consensus statement of a working party of the Indian National Association for Study of the Liver. J Gastroenterol Hepatol. 2010 Jun;25(6):1029-1041.
  • Singh S, Gupta R, Malhotra V, Sarin SK. Predictors of histological activity and fibrosis in chronic Hepatitis C infection: a study from North India. Indian J Pathol Microbiol. 2010 Apr-Jun;53(2):238-43
  • Mishra SR, Chander Sharma B, Kumar A, Sarin SK. Endoscopic cyanoacrylate injection versus beta-blocker for secondary prophylaxis of gastric variceal bleed: a randomised controlled trial. Gut. 2010 Jun;59(6):729-35
  • Sarin SK, Gupta N, Jha SK, Aggarwal A, Mishra SR, Sharma BC, Kumar A. Equal Efficacy of Endoscopic Variceal Ligation and Propranolol in Preventing Variceal Bleeding in Patients with Non-Cirrhotic Portal Hypertension. Gastroenterology. 2010 Oct;139(4):1238-45.
  • Singh DK, Rastogi A, Sakhuja P, Gondal R, Sarin SK. Comparison of clinical, biochemical and histological features of alcoholic steatohepatitis and non-alcoholic steatohepatitis in Asian Indian patients. Indian J Pathol Microbiol. 2010 Jul-Sep;53(3):408-13
  • Thakur V, Pati NT, Gupta RC, Sarin SK.Efficacy of Shanvac-B recombinant DNA hepatitis B vaccine in health care workers of Northern India. Hepatobiliary Pancreat Dis Int. 2010 Aug;9(4):393-7.
  • Sarin SK, Mishra SR. Endoscopic therapy for gastric varices. Clin Liver Dis. 2010 May;14(2):263-79.
  • de Franchis R; Baveno V Faculty. Revising consensus in portal hypertension: report of the Baveno V. consensus workshop on methodology of diagnosis and therapy in portal hypertension. J Hepatol. 2010 Oct;53(4):762-8.
  • Omata M, Lesmana LA, Tateishi R, Chen PJ, Lin SM, Yoshida H, Kudo M, Lee JM, Choi BI, Poon RT, Shiina S, Cheng AL, Jia JD, Obi S, Han KH, Jafri W, Chow P, Lim SG, Chawla YK, Budihusodo U, Gani RA, Lesmana CR, Putranto TA, Liaw YF, Sarin SK. Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma. Hepatol Int. 2010 Mar 18;4(2):439-74.
  • Sharma P, Agrawal A, Sharma BC, Sarin SK.Prophylaxis of Hepatic Encephalopathy in Acute Variceal Bleed: A Randomized Controlled Trial of Lactulose versus no Lactulose. J Gastroenterol Hepatol. 2010 Dec 6.
  • Mishra SR, Sharma BC, Kumar A, Sarin SK. Primary Prophylaxis of Gastric Variceal Bleeding Comparing Cyanoacrylate Injection and Beta-blockers: A Randomized Controlled Trial. J Hepatol. 2011 Jun;54(6):1161-7.
  • Sukriti S, Pati NT, Bose S, Hissar SS, Sarin SK. Impaired Antigen Processing and Presentation Machinery is Associated with Immunotolerant State in Chronic Hepatitis B Virus Infection. J Clin Immunol. 2010 May;30(3):419-25.
  • Kumar A, Mishra SR, Sharma P, Sharma BC, Sarin SK. Clinical, Laboratory, and Hemodynamic Parameters in Portal Hypertensive Gastropathy: A Study of 254 Cirrhotics. J Clin Gastroenterol. 2010 Apr;44(4):294- 300.
    2009
  • Pande C, Kumar A, Sarin SK. Small Intestinal Bacterial Overgrowth In Cirrhosis Is related To Severity Of Liver Disease. Aliment Pharmacol Ther. 2009 Jun 15;29(12):1273-81.
  • Sharma P, Sharma BC, Puri V, Sarin SK. .Natural history of minimal hepatic encephalopathy in patients with extrahepatic portal vein obstruction. Am J Gastroenterol. 2009 Apr;104(4):885-90
  • Kumar M, Chauhan R, Gupta N, Hissar S, Sakhuja P, Sarin SK. Spontaneous increases in alanine aminotransferase levels in asymptomatic chronic hepatitis B virus-infected patients. Gastroenterology. 2009 Apr;136(4):1272-80
  • Kumar GT, Kazim SN, Kumar M, Hissar S, Chauhan R, Basir SF, Sarin SK. Hepatitis B virus genotypes and hepatitis B surface antigen mutations in family contacts of hepatitis B virus infected patients with occult hepatitis B virus infection. J Gastroenterol Hepatol. 2009 Apr;24(4):588-98.
  • TrehanPati N, Geffers R, Sukriti, Hissar S, Riese P, Toepfer T, Buer J, Kumar M, Guzman CA, Sarin SK.Gene expression signatures of peripheral CD4+ T cells clearly discriminate between patients with acute and chronic hepatitis B infection. Hepatology. 2009 Mar;49(3):781-90
  • Sharma P, Kumar A, Sharma BC, Sarin SK. Infliximab monotherapy for severe alcoholic hepatitis and predictors of survival: an open label trial. J Hepatol. 2009 Mar;50(3):584-91.
  • Suneetha PV, Schlaphoff V, Wang C, Stegmann KA, Fytili P, Sarin SK, Manns MP, Cornberg M, Wedemeyer H. Effect of peptide pools on effector functions of antigen-specific CD8+ T cells. J Immunol Methods. 2009 Mar 15;342(1-2):33-48
  • Kumar M, Choudhury A, Manglik N, Hissar S, Rastogi A, Sakhuja P, Sarin SK. Insulin resistance in chronic hepatitis B virus infection. Am J Gastroenterol. 2009 Jan;104(1):76-82.
  • Sharma BC, Sharma P, Agrawal A, Sarin SK. Secondary Prophylaxis of Hepatic Encephalopathy: An Open Label Randomized Controlled Trial of Lactulose Versus Placebo.Gastroenterology. 2009 Jun 4.
  • Kumar A, Jha SK, Sharma P, Dubey S, Tyagi P, Sharma BC, Sarin SK. Addition of Propranolol and Isosorbide Mononitrate to Endoscopic Variceal Ligation Does Not Reduce Variceal Rebleeding Incidence. Gastroenterology 2009 Sep;137(3):892-901
  • Hissar SS, Kumar M, Tyagi P, Goyal A, Suneetha PV, Agarwal S, Rastogi A, Sakhuja P, Sarin SK. Natural history of hepatic fibrosis progression in chronic hepatitis C virus infection in India. J Gastroenterol Hepatol. 2009 Apr;24(4):581-7.
  • Sharma BC, Agarwal N, Sharma P, Sarin SK. Endoscopic biliary drainage by 7 Fr or 10 Fr stent placement in patients with acute cholangitis. Dig Dis Sci. 2009 Jun;54(6):1355-9.
  • Sharma P, Sharma BC, Tyagi P, Kumar M, Sarin SK. Neuropsychological impairment in severe acute viral hepatitis is due to minimal hepatic encephalopathy. Liver Int. 2009 Feb;29(2):260-4. Epub 2008 Aug 14.
  • Kumar A, Das K, Sharma P, Mehta V, Sharma BC, Sarin SK. Hemodynamic studies in acute-on-chronic liver failure. Dig Dis Sci. 2009 Apr;54(4):869-78. Epub 2008 Aug 9.
  • Saini V, Madan K, Mittal VV, Sakhuja P, Sarin SK.Alpha-fetoprotein production by non-hepatocellular carcinoma, malignant liver tumor. Indian J Cancer. 2009 Jul-Sep;46(3):253-4
  • Kumar M, Sarin SK, Sarin SK. Hepatitis B Virus Immunotolerant Patients: Need to Differentiate Patients With or Without Liver Disease? Gastroenterology. 2009 Jun 26.
  • Sharma P, Sharma BC, Sarin SK. Predictors of nonresponse to lactulose for minimal hepatic encephalopathy in patients with cirrhosis. Liver Int. 2009 Jun 23.
  • Sharma P, Kumar A, Sharma BC, Sarin SK. Early identification of haemodynamic response to pharmacotherapy is essential for primary prophylaxis of variceal bleeding in patients with 'high-risk' varices.Aliment Pharmacol Ther. 2009 Jul;30(1):48-60.
  • Sarin SK, Kumar A, Almeida JA, Chawla YK, Fan ST, Garg H, de Silva HJ, Hamid SS, Jalan R, Komolmit P, Lau GK, Liu Q, Madan K, Mohamed R, Ning Q, Rahman S, Rastogi A, Riordan SM, Sakhuja P, Samuel D, Shah S, Sharma BC, Sharma P, Takikawa Y, Thapa BR, Wai CT, Yuen MF. Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL). Hepatol Int. 2009 Mar;3(1):269-82.
  • Jha SK, Kumar A, Sharma BC, Sarin SK. Systemic and pulmonary hemodynamics in patients with extrahepatic portal vein obstruction is similar to compensated cirrhotic patients. Hepatol Int. 2009 Jun;3(2):384-91.
  • Manohar K, Suneetha PV, Sukriti, Pati NT, Gupta AC, Hissar S, Sakhuja P, Sarin SK. Association of IL-18 promoter polymorphism with liver disease severity in HCV-infected patients.Hepatol Int. 2009 Jun;3(2):371-7.
  • Shiha G, Sarin SK, Ibrahim AE, Omata M, Kumar A, Lesmana LA, Leung N, Tozun N, Hamid S, Jafri W, Maruyama H, Bedossa P, Pinzani M, Chawla Y, Esmat G, Doss W, Elzanaty T, Sakhuja P, Nasr AM, Omar A, Wai CT, Abdallah A, Salama M, Hamed A, Yousry A, Waked I, Elsahar M, Fateen A, Mogawer S, Hamdy H, Elwakil R; Jury of the APASL Consensus Development Meeting 29 January 2008 on Liver Fibrosis With Without Hepatitis B or C. Liver fibrosis: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL). Hepatol Int. 2009 Jun;3(2):323-33.
  • Sharma BC, Mishra SR, Kumar R, Sarin SK. Endoscopic management of bile leaks after blunt abdominal trauma. J Gastroenterol Hepatol. 2009 May;24(5):757-61.
  • Sharma P, Sharma BC, Tyagi P, Kumar M, Sarin SK. Neuropsychological impairment in severe acute viral hepatitis is due to minimal hepatic encephalopathy. Liver International. 2009 Feb;29(2):260-4
  • Madhusudana Girija Sanal, Shiv K Sarin. Serum adipokine profile in Indian men with nonalcoholic steatohepatitis: Serum adiponectin is paradoxically decreased in lean vs. obese patients. Diabetes & Metabolic Syndrome: Cliical Research & Reviewes 2009;3: 198-203.