Characterized Animal Models available at ILBS
Institute of Liver and Biliary Sciences (ILBS) is an autonomous super-specialty Institute of excellence under GNCT of Delhi and a Deemed-to-be-University by the UGC. Its vision is to be a global leader by becoming a beacon of patient care, teaching and research in the field of Liver, Gall Bladder and pancreatobiliary diseases.
| Types of Animal Models | Name of Model | Species |
|---|---|---|
| Liver Fibrosis/Cirrhosis | CCL4 & it's variants (Fibrotic, Cirrhotic-Compensated & decompensated) | Mouse, Rat |
| Thiacetamide induced liver injury | Mouse, Rat | |
| Cholestatic Liver Cirrhosis models | CBDL | Mouse, Rat |
| PHT (portal hypertension) | PPVL (Partial Portal vein ligation) | Mouse |
| CCL4 & it's variants (Fibrotic, Cirrhotic-Compensated & decompensated) | Mouse, Rat | |
| Thiacetamide induced liver injury | Mouse, Rat | |
| CBDL | Mouse, Rat | |
| Diet Induced Liver Diseases model | NASH/NAFLD (MCD and HFD Diet) – On going | Mouse , Rat |
| ACLF | ACLF | Mouse, Rat |
| CBDL induced HPS Model | CBDL | Mouse (Sukriti.Baweja,Anupma Kumari et.al. J.Heptology, 2023) |
| Hepatoencephalopathy Model | Thioacetamide (TAA) induced acute hyperammonemia model | Rat |
| Gallstone Model | DCA-HFHCD Diet Induced | Mouse |
| Sepsis | Sepsis-LPS (lipopolysachharides) | Mouse, Rat |
| HCC Model | DEN | Mouse |
