• Institute of Liver and Biliary Sciences (ILBS).
• Senior Research Fellow in Institute of Liver and Biliary Sciences (ILBS) (2011-2013).

Awards/ Membership (Till Date):

• Member of Scientific Advisory Committee of Laboratory Animal Scientist’s Association (India).
• CCSEA Member in IAECs
• All India Rank-8^th for M.V.SC (DBT-CET-2008).
• DBT Fellowship for M.VSc. (Animal Biotechnology) Programme.
• Awarded UGC-CSIR-LS NET (AI-62 Rank) in Life Sciences (December 2009).

Investigating pathobiological mechanisms of liver diseases and regeneration and developing therapeutic strategies using preclinical models.

Research Work

Laboratory Animal Science, Animal Model of Liver Diseases, Refinement of Aseptic Rodent Surgical Procedures. Assisted Reproduction Technology in Rodents.

Research Project/Grants:

• Co-Principal Investigator: Three Dimensional (3D) Neuro-Hepatic Map and functions of hepatic neuronal. Approved(Ongoing) - SERB-DST -60L
• Co-Principal Investigator: Designing bacterial Exosomes Cargo for targeting specific cells of Liver cancer. Ongoing: Global Star Call proposal - DBT -1.78 Cr
• Co-Principal Investigator: Hepatic Neuroanatomy and Functions In Physiology & Pathophysiology. Completed: PhD Thesis (2021-2024).
• Co-Principal Investigator: A Randomised, Open Label Trial To Study The Efficacy Of Mebendazole In Addition To Lenvatinib In Patients Of Cirrhosis With Unresectable Hepatocellular Carcinoma. Completed: DM-Heptatology Thesis (2019-2022).
• Co-Principal Investigator: Development of non-transplant therapeutic strategies for advanced liver diseases phase-I Completed (2018-2021): DST-Mega project-5.5 Cr

In-Vivo Research  & Support Services:

• Technical expertise in Designing and implementation  of “Animal Care and Use programe” including ABSL3 as per national (CCSEA,MOFA&H, GOI) and international regulatory standards such as Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International, USA) , Good Laboratory Practices- Organisation for Economic Co-operation and Development (GLP-OECD), Federation of European Laboratory Animal Science Associations (FELASA), American Veterinary Medical Association (AVMA), Biosafety in Microbiological and Biomedical Laboratories (BMBL,CDC,NIH) and Institutional Biosafty Committee (IBSC-DBT,GOI) etc. for Biomedical research and Biosafty guidelines. 
• Breeding and Maintenance of SPF and Immunodeficient laboratory animals (Rodents,Rabbits,Zebrafish etc.) for biomedical research. 
• Expertised in Aseptic Rodent survival surgery such as Common Bile duct ligation (CBDL), 2/3rd Partial Hepatectomy, Caecal Ligation Puncture (sepsis model), Spleenectomy, Assisted Reproductive Techniques (Egg collection, Embryo transfer, ovariohysterectomy, Vasectomy etc.) & biomethodologies (Oral gavage, IP,SC,IV,IM,ID and blood collection , organ Perfusion and tissue collection) animal experimental procedures by applying 3Rs and veterinary care practices for ABSL2 and ABSL3.
• Expertised in Molecular Biology Techniques (RTPCR, Bioanalyzer, Gel Electrophoresis, Clonning etc), Cell Culture and Immune cell Isolation  and FACS, Immunihistochemistry,ELISA. etc.
• Expertised in Microscopy and In-vivo Imaging Techniques on Optical imaging Model Perkin Elmer IVIS LUMINA XRMS as well as  LAGO- Spectral Imaging Instrument, and micro-CT .
• Establishment of Pig research Facility.

Accreditation & Regulatory Compliance:

• Member and Co-ordinator of Institutional Animal Ethics Committee (IAEC).
• Regulatory Compliance for Pre-clinical Facility Establishment and Operation as per national and international rules and regulations (CPCSEA, 2018 & NRC 2011). 
• Laboratory Animal Transport/Import.

Name of the conf./course/training/workshop attended:

• Oral Presentation on “Jet Lag Mouse fed on high fat diet shows fatty liver changes associated and partly reversed when fed with Nicotinamide Riboside” in 11^th International Conference of Laboratory Animal Scientists’ Association (LASA), India, on “Advancements of 3R’s in Biomedical Research and Laboratory Animal Science and Welfare: International Perspectives” 6-8^th November,2023,IISC, Bangaluru.
• Oral Turbo Talk on “Triple humanized mouse model: Next generation tool for malaria research ” in the International Conference  on Vector Borne Diseaes (NAVBD)  at GOA University,15^th-17^th Feb,2023.
• Oral Presentation on “A Common Bile Duct Ligation (CBDL) induced mice model of Hepato-Pulmonary syndrome (HPS).” in 10^th International Conference of Laboratory Animal Scientists’ Association (LASA), India, on “Animal Models for One Health Programme: Challenges and Future Perspectives” 3-4^th June 2022 at NAARM Hydrabad
• Participated in certificate course of One week training in “Mouse Microinjection and CRISPER/CAS” held at National Centre for Biological Scineces (NCBS), Bangalore, India, Oct 21^st-25^th, 2019.
• Participated in “IACUC/IAEC training: The AAALAC International Perspective” organized by ACTREC, Navi Mumbai (Oct-2015).
• Undergone Certification FELASA ‘C’  “Certificate Course in Laboratory Animal Sciences” of 80 Credit Hrs under the Mentorship of FELASA Congress Chairperson Dr. Patri Vergara held at TANUVAS jointly organized by NIAW,CPCSEA and LASA from 14^th - 23^rd September 2013 in Chennai, TN.
• Participated in  “One Week Training of CPCSEA Nominee” at NIAW, Ballabhgarh, Faridabad (Jan 2015).
• Undergone One Month Training in “Advance Training in Care, Breeding, Management, Health monitoring and Quality Control of Laboratory Animals” from 9th December 2011 to 8^th January 2012 at NLAC, CDRI, Lucknow.

Conferences and Invited Lectures:

• Organizing Secretary of  Four days Hands-on Workshop on “Basic Training in Animal Handling and Experimentation organized from last five years on 1^st- 4^th Novemeber-2023, 2^nd -5^th November-2022, 27^th  -30^th July-2021, 17^th -20^th Feb-2020 and  10^th -13^th July ,2019  at ILBS, New Delhi.
• Organizing Secretary of ‘Rodent Surgery Workshop’ organized on 1-3^rd June, 2023 and 25^th-27^th April,2024  at ILBS, New Delhi.
• Imparted Training and Lecture  in One week Workshop on “Workshop for Handling and Care of Laboratory Animals” on  28^th Nov-2^nd December,2023, 14^th-17^th Nov,2022 & 20-24^th Feb,2022 at JNU,New Delhi as a Resource Faculty  Member.
• Invited Lecture on “Refinement in Rodent Survival Surgery and Terminal Procedures” and imparted training as a Resource Faculty Member on “Aseptic Rodent Survival Surgery” in TPLAS, 27^th Oct-2^nd November, 2023 organized by Dept.of Pharmacy, BITS, Pillani Rajasthan.
• Imparted Training as a Resource Faculty Member in “Two weeks Certificate Course on  Laboratory Animal Sciences” from  6-17^th Feb 2023 at NBRC. Manesar, Haryana.
• Invited Speaker and Resource Person in "National Workshop on Animal Biosafety Level-2 (ABSL-2) practices" from 16th-17th May, 2022 at Jamia  Hamdard, New delhi.
• Invited Lecture on “Euthanasia and Necropsy Procedure in Lab Animal Experimentations” imparted training as a Resource Faculty Member in 5^th Course on Lab Animal Sciences (CLAS),  11^th-16^th April, 2024 organized by   IGIB, New Delhi.

1. Book Chapter on “Animal Models in Cancer Research: Bridging the gap between Bench and Bedside”. Zaid Shaikh, Sakshi Anchan, Anupama Kumari and Rahul Thorat. Animal Models in Research: Principles and Practice, Publisher Springer Nature, ISBN-13 978-9819700479,1^st edition 2024 (5^th April,2024).
2. Fingolimod In HPS: Assess and Then Judge, a Potential Ray of Hope. Sukriti Baweja ^, Chhagan Bihari, Anupama Kumari, Dinesh Mani Tripathi, Shiv Kumar Sarin; Journal of Hepatology, July 2023. DOI: 10.1016/j.jhep.2023.07.024.
3. Lipopolymeric nanocarrier enables effective delivery of CRISPR/Cas9 expressing plasmid. Deepak Kumar Sahel, Sangam Giri Goswami, Reena Jatyan, Anupma Kumari, Anupama Mittal, Sivaprakash Ramalingam and Deepak Chitkara; April 2023 Macromolecular Rapid Communications, DOI: 10.1002/marc.202300101. [ IF-5.006]
4. Hepatopulmonay syndrome is associated with low sphingosine-1-phosphate levels and can be ameliorated by the functional agonist fingolimod. Sukriti Baweja, Anupama Kumari, Preeti Negi, Arvind Tomar, Dinesh Mani Tripathi, Akash Kumar Mourya,  Aayushi Rastogi, Swati Thangariyal,  P. Debishree Subudhi, Shivani Gautam, Ashmit Mittal, Guresh Kumar, Jitendra Kumar, G. Srinivasa Reddy, Arun Kumar Sood, Chitranshu Vashistha, Vivek Sarohi, Chhagan Bihari., Rakhi Maiwall, Shiv Kumar Sarin; Journal of Hepatology,2023 DOI: 10.1016/j.jhep.2023.03.018. [IF- 30.083]
5. Vascular Extracellular Vesicles Indicate Severe Hepatopulmonary Syndrome in Cirrhosis. Sukriti Baweja , Anupama Kumari, Preeti Negi ,Swati Thangariyal ,P. Debishree Subudhi ,Shivani Gautam ,Ashmit Mittal  and Chhagan Bihari; Diagnostics 2023, 13(7), 1272. [IF -4.129]
6. Immunonano-Lipocarrier-Mediated Liver Sinusoidal Endothelial Cell-Specific RUNX1 Inhibition Impedes Immune Cell Infiltration and Hepatic Inflammation in Murine Model of NASH. Tripathi DM, Rohilla S, Kaur I, Siddiqui H, Rawal P, Juneja P, Kumar V, Kumari A, Naidu VGM, Ramakrishna S, Banerjee S, Puria R, Sarin SK, Kaur S; Int J Mol Sci. 2021 Aug 6;22(16):8489.[IF-6.208]
7. Circulating Microvesicle Induced Monocyte Dysfunction Is Associated With Sepsis And High Mortality In Cirrhosis. Sukriti S, Bihari C, Negi P, ThangariyalS, Kumari A, Lal D, Maheshwari D, , Singh MJ, Nautiyal N, Kumar G, Kumar A, Trehanpati N,  Mehta G, Chaudhary AK^, Maiwal R, Sarin SK; Liver Int. 2021 Jul;41(7):1614-1628. [IF-8.754]
8. Establishment of a murine model of acute-on-chronic liver failure with multi-organ dysfunction.Nautiyal N, Maheshwari D, Tripathi DM, Kumar D, Kumari R, Gupta S, Sharma S, Mohanty S, Parasar A, Bihari C, Biswas S, Rastogi A, Maiwall R, Kumar A, Sarin SK; Hepatol Int . 2021 Dec; 15(6):1389-1401.[IF-9.046]
9. Hepatitis B Virus Induces Cell Proliferation via HBx-Induced microRNA-21 in Hepatocellular Carcinoma by Targeting Programmed Cell Death Protein4 (PDCD4) and Phosphatase and Tensin Homologue (PTEN). P.Damania, B.Sen,S.B.Dar, S.Kumar, A.Kumari, E.Gupta, S.K.Sarin, S.K.Venugopal; PLOS, March 2014. [IF-3.754]
10. Key elements of RNAi pathways are regulated by Hepatitis B virus replication and HBx acts as a viral suppressor of RNA silencing. M. Chinappan, A.K Singh, P.K. Kakumani G.Kumar, S.B. Rooge, A.Kumari, A.Varshney, A.Rastogi, S.K.Sarin, P.Malhotra, R.K.Bhatnagar; Biochemical Journal, 2014. [IF -3.766].
11. Sequential Therapy with Tenofovir plus Peg Interferon Enhances Innate and Adaptive Immunity compared to tenofovir monotherapy in chronic hepatitis B patient. Nirupma Trehanpati, Arshi Khanam, S. Syed Hissar, Rashi Sehgal, Ritu Khosla, Paul David, Ashish Kumar Vyas, Anupama Parashar, Ankit Bhardwaj Shyam Kottillil and Shiv Kumar Sarin. Journal of Clinical & Cellular Immunology, 2014. [IF-3.146]