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Speciality

Haematology

Dr. Chhagan Bihari  
Dr. Chhagan Bihari
Professor
 
Year of last degree
2008
Experience

Dr. Bihari Completed MD pathology from SMS Medical College. His  areas of interest are Oncopathology, Vascular liver diseases, and Bone marrow dysfunction in liver diseases. Currently working as Additional Professor, Pathology at ILBS.

Qualification

Dr. Chhagan Bihari is working as Professor of Pathology, and in charge of Laboratory Hematology, Biobank, and Research and Development Cell at ILBS. He has an experience of >15 years in the field of liver pathology and transplant pathology. He was able to publish 184 indexed articles in prestigious journals- Hepatology, Journal of Hepatology, Hepatology Communications, Histopathology, Human Pathology, APMIS, and Frontiers etc. He is an editor of one book and has been guest editor of four journals issues and wrote 6 book chapters. Dr. Bihari had 10 extramural projects with overall funding of approximately 40 crores. He was able to establish National Liver Disease Biobank, covid-19 biorepository, and a sequencing service facility at the institute. He received an outstanding achievement award in the field of biobanking in India, Innovation in Health award 2018 and collaborative training award ISTH. He facilitated academia-industry collaboration for sustainable platforms. He is a member of SRRB, and member secretary of biobank committee. Our biobank is first ever CTRnet-certified and ISO accredited biobank in India. We have also started new courses in PDCC hepatopathology, liver hematology and biobank certificate course. We were able to develop a biosamples management software which has the copyright.

Number of publications
184
Awards
  • DST Travel Grant
  • Best Senior Resident presentation in ILBS-Clinics, 2011
  • Oral Presentations APASL AASLD, EASL
  • Outstanding achievement in biobanking,
  • Copyright BIMS
  • ISO & CTRnet accreditations of Biobank
Research Int

Liver Pathology, Coagulation and Hematopoiesis in Liver Diseases

Trainings

APDW 2017, Hong Kong

AASLD 2017 Washington DC, USA

Nanfang Hospital, Southern Medical University, Guangzhou, China

National Biobanking Workshop, TMC Kolkata, India

Training at TMH, Mumbai

Training at UPMC, USA

Total number of Projects in which the faculty member is PI (Till date) : 10

S.No. Project Title Funding Agency StartDate
1 Identification of Novel Biomarkers fordiagnosis and prognosis of Autoimmune Hepatitis SERB 23.86 2018- 2020
2 National Liver Disease Biobank DBT 2222 2016- 2022
3 Covid-19 biorepository DBT 148 2021- 2023
4 INSACOG DBT 375 2021-2023
5 Covid Seq Program (Co-PI) GNCTD 1240 2021-2023
6 Extracellular Vesicles in Autoimmune Hepatitis DBT 49.56 2021-2024.
7 Oral-Liver Axis in Liver Transplant Recipients ICMR 99.6 2021-2024
8 Oral Microbiome as predictor of eventual progression of liver cirrhosis ILBS-IIT 57.6 Ongoing
9 Urinary signatures of Severe Covid in chronic diseases ICMR 72.4 Ongoing
10 SBP rapid detection panel ICMR 107 Sanctioned
Publications
  • Total Publications: 184
  • Total Number of publications in 2024: 14
  • Extramural Projects: 8
  • Edited Book: 1
  • Book Chapters: 5

Recent Publications: 17

1. Shukla, A., Rockey, D.C., Kamath, P.S....Bihari C...Sarin SK. Non-cirrhotic portal fibrosis/idiopathic portal hypertension: APASL recommendations for diagnosis and management. Hepatol Int 18, 1684–1711 (2024).

2. Bihari C, Dhariwal S, Shasthry SM, et al Dissociation in hepatic vein pressure gradient, liver stiffness measurement and complications in histological subtypes of porto-sinusoidal vascular disease Journal of Clinical Pathology Published Online First: 19 January 2024. doi: 10.1136/jcp-2023-209321.

3. Sharma, Sachin; Ghufran, Shaikh Maryam; Aftab, Mehreen; Bihari, Chhagan; Ghose, Sampa; Biswas, Subhrajit; Survivin inhibition ameliorates liver fibrosis by inducing hepatic stellate cell senescence and depleting hepatic macrophage population Journal of Cell Communication and Signaling 18 1 e12015 2024 .

4. Kumar, Manoj; Venishetty, Shantan; Jindal, Ankur; Bihari, Chhagan; Maiwall, Rakhi; Vijayaraghavan, Rajan; Muralikrishna, Shasthry Saggere; Arora, Vinod; Kumar, Guresh; Sarin, Shiv K; Tranexamic acid in upper gastrointestinal bleed in patients with cirrhosis-a randomized controlled trial Hepatology 10.1097 2024

5.Chhabra, Ruchita; Agarwal, Reshu; Gautam, Pramod; Suroliya, Varun; Thappar, Shalini; Shastry, SM; Tomar, Arvind; Bihari, Chhagan; Kale, Pratibha; Pamecha, Viniyendra; SARS-CoV-2 among liver transplant recipients: Clinical course and mutational analysis Journal of Clinical Virology Plus 4 100181 2024.

6. Varadarajan, Annapoorani; Rastogi, Archana; Maiwall, Rakhi; Bihari, Chaggan; Thomas, Sherin; Shasthry, Saggere Muralikrishna; Serum IgG level in autoimmune liver diseases and its significance: Is there a need to revisit existing criteria? Experience from a tertiary care center Indian Journal of Pathology and Microbiology 10.4103 2024

7. Agrawal, Neha; Rastogi, Archana; Bihari, Chhagan; Choudhury, Ashok; Pamecha, Viniyendra; Plasma Cell Infiltrate in Liver Allograft Biopsy: Clinical and Histological ImplicationsIndian Journal of Transplantation 18 2 144-150 2024 Medknow.

8. Nautiyal, Nidhi; Maheshwari, Deepanshu; Kumar, Dhananjay; Rao, E Pranshu; Tripathi, Dinesh Mani; Kumar, Sandeep; Diwakar, Sunidhi; Bhardwaj, Manisha; Mohanty, Sujata; Baligar, Prakash; Rejuvenating bone marrow hematopoietic reserve prevents regeneration failure and hepatic decompensation in animal model of cirrhosis Frontiers in Immunology15 1439510 2024 Frontiers Media SA

9. Agarwal, Reshu; Bhugra, Arjun; Gautam, Pramod; Suroliya, Varun; Chhabra, Ruchita; Pandey, Amit; Garg, Prince; Rao, Pooja; Babu, Rosmy; Kumar, Guresh; Clinical and Genomic Perspective of SARS CoV-2 Infection in Liver Disease Patients: A Single-Centre Retrospective Study Current Microbiology 81 9 301 2024 Springer US New York.

10. Nautiyal, Nidhi; Maheshwari, Deepanshu; Chauhan, Shivi; Bhardwaj, Manisha; Diwakar, Sunidhi; Maras, Jaswinder SIngh; Kumari, Anupama; Biswas, Subhrajit; Bihari, Chhagan; Sarin, Shiv K; Nicotinamide riboside (NR) supplementation enhances bacterial elimination and reduces fibrosis in an animal model of cirrhosis Journal of Clinical and Experimental Hepatology 142024 Elsevier

11. Koshy, Ashily; Yadav, Abhilasha; Rastogi, Archana; Agrawal, Neha; Bihari, Chhagan; Ramakrishna, Gayatri; Kumar, Guresh; Pamecha, Viniyendra; Clinico-pathological study of intra-hepatic cholangiocarcinoma Journal of Clinical and Experimental Hepatology 14 2024 Elsevier.

12. Maheshwari, Deepanshu; Nautiyal, Nidhi; Bhardwaj, Manisha; Diwakar, Sunidhi; Chauhan, Shivi; Sharma, Nikita; Kumari, Anupama; Rastogi, Archana; Bihari, Chhagan; Sarin, Shiv Kumar; Gut Barrier Dysfunction-Induced Endotoxemia Leads to Metabolic Dysfunction in Hematopoietic Stem Cells, Resulting in Impaired Macrophage Production and Depletion of the Liver Macrophage Pool Journal of Clinical and Experimental Hepatology 14 2024

13. Vashishtha, Chitranshu; Bhardwaj, Ankit; Agarwal, Prashant M; Bihari, Chhagan; Correlation Between Clinical Assessment and Postmortem Lung Biopsy in Patients With Pulmonary Infiltrates and Respiratory Failure Cureus 16 9 e70014 2024.

14. Nigam, Neha; Yadav, Rajanikant; Pandey, Gaurav; Hashim, Zia; Bihari, Chhagan; Vishwadeep, Rana; Kumar, Nirbhay; Mishra, Prabhakar; The histological grading of fibrosis in Budd-Chiari syndrome: A chronic liver disease, different from others Indian Journal of Gastroenterology 01-Oct 2024 Springer India New Delhi

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