• Researcher (R2), IDIBAPS, Hospital Clinic Barcelona, Barcelona, Spain (Nov 2016-July 2018)
• Sheila Sherlock Post-doctoral Fellow IDIBAPS, Hospital Clinic Barcelona, Barcelona, Spain (Nov 2014-Oct 2016)
• DST Senior Research Fellow, Institute of Liver and Biliary Sciences (ILBS), New Delhi (July2010-Oct 2014)
• DST Junior Research Fellow, GB Pant Hospital, Maulana Azad Medical College, University of Delhi, New Delhi (July2007-June 2010)
• Research Assistant, National Institute of Malaria Research (NIMR) Delhi, New Delhi (Aug 2006- March 2007)

AASLD Foundation International Early Career Investigator Award in the AASLD 2020 International Conference, USA.
Young investigator travel award in The Liver Sinusoid Meeting: 20th International Symposium on Cells of the Hepatic Sinusoid (ISCHS 2019), Sydney, Australia.
Best Paper Presentation Award ASOCIACIÓN ESPAÑOLA DE ESTUDIO DEL HÍGADO, 2016.
Awarded with “Young Investigator Award 2015” in the Indian Society for Gastroenterology ISGCON 2015, Mumbai, India.
Awarded with “EASL- Sheila Sherlock Post-Doc Fellowship” European Association for the Study of Liver, at ILC 2014, London, UK.
Awarded with the “ICMR-Young scientist International Travel-grant” to attend and present the study in 2014.
Awarded with “Young Investigator Travel award” at AASLD Liver Meeting 2013 Washington DC, USA.
Selected for “Young Investigator Award” at EASL-ILC 2012, Barcelona, Spain.
Awarded with “The Liver Care Foundation” at Asia Pasific Association Study for Liver 2012 Annual Conference, Taiwan.
Best Poster Presentation in “MOLECULAR MEDICINE UPDATE – 2008” organized by Maulana Azad Medical College, New Delhi.

Our research group focusses on “Pre-clinical research and drug discovery for Liver Fibrosis and Portal Hypertension". We work in the area of Hepatic cell biology, both parenchymal (Hepatocyte, cholangiocytes) and non-parenchymal (Hepatic stellate and endothelial cells) and study its phenotype in regulating the intrahepatic microenvoirnment in diseased liver. We have developed primary hepatic cell repository to understand its role in diseases pathogenesis and also to explore biomaterials based hybrid scaffold functioning in the field of tissue engineering. We have advanced in characterizing the hepatic and ductual organoids under Microfluidic dynamic culture platform for pre-clinical research. Our group has expertise in development of pre-clinical animal models for translational studies in the field of liver cirrhosis, portal hypertension, liver regeneration and Acute-on-chronic liver failure. Liver Physiology & Vascular Biology Lab has state-of-art facility for pre-clinical research in Hepatic Hemodynamic. Our research finding deciphers new therapeutic targets for liver cirrhosis and its associated complications. Our various research findings have proposed new therapies that improve hepatic microcirculation, fibrosis and liver regeneration.

Non-cirrhotic and cirrhotic Portal Hypertension, Hepatic hemodynamic, Liver Fibrosis, Hepatic tissue engineering, Mechano-theraputics, Hepatic organoid biology, Pre-clinical animal models for liver cirrhosis, portal hypertension, liver regeneration and Acute-on-chronic liver failure, NAFLD.

1. American association study of liver disease (AASLD 2020) International Conference, USA.

2. The Liver Sinusoid Meeting: 20th International Symposium on Cells of the Hepatic Sinusoid (ISCHS 2019), Sydney, Australia.

3. Indian Society for Gastroenterology ISGCON 2019, Kolkata, India.

4. Asia Pacific Association Study for Liver 2018 Annual Conference, Delhi India.

5. International Liver congress 2016-European Association for the Study of Liver, at Barcelona, Spain

6. ASOCIACIÓN ESPAÑOLA DE ESTUDIO DEL HÍGADO, 2016.

7. International Liver congress 2015-European Association for the Study of Liver, at Vienna, Austria

8. Indian Society for Gastroenterology ISGCON 2015, Mumbai, India.

9. International Liver congress 2014-European Association for the Study of Liver, at London, UK.

10. American association study of liver disease AASLD Liver Meeting 2013 Washington DC, USA.

11. International Liver congress -ILC 2012, European Association for the Study of Liver Barcelona, Spain.

12. Asia Pasific Association Study for Liver 2012 Annual Conference, Taiwan.

• 1. De S, Vasudevan A, Tripathi DM, Kaur S, Singh N. A decellularized matrix enriched collagen microscaffold for a 3D in vitro liver model. J Mater Chem B. 2024;12(3):772
• 2. Syamprasad NP, Siddhi Jain, Bishal Rajdev, Samir Ranjan Panda, Gangasani Jagadeesh Kumar, Khaja Moinuddin Shaik, PA Shantanu, Veerabhadra Swamy Challa, Sachin B Jorvekar, Roshan M Borkar,Jayathirtha Rao Vaidya, Dinesh Mani Tripathi*, VGM Naidu* AKR1B1 drives hyperglycemia-induced metabolic reprogramming in the initiation and progression of MASLD-associated hepatocellular carcinoma. JHEP Rep. 2023
• 3. Preety Rawal , Dinesh M Tripathi, Hamed Hemati, Jitender Verma, Shiv K Sarin , Vikrant Nain, Savneet Kaur Targeting HBx by CRISPR/Cas9 system effectively reduces epithelial to mesenchymal transition in hepatoma cells. Liver Int. 2023 Nov 23. 
• 4. Baweja S, Bihari C, Kumari A, Tripathi DM, Sarin SK. Reply to: Correspondence on "Hepatopulmonary syndrome is associated with low sphingosine-1-phosphate levels and can be ameliorated by the functional agonist fingolimod". J Hepatol. 2023 Nov;79(5) 
• 5. Campreciós G, Vilaseca M, Tripathi DM*, Montironi C, Díaz A, Aguilar D, García-Calderó H, Montañés R, Anton A, Hernández-Gea V, García-Pagán JC. Interspecies transcriptomic 4 comparison identifies a potential porto-sinusoidal vascular disorder rat model suitable for in vivo drug testing.Liver Int. 2023 Oct 23. 
• 6. Vasudevan A, Majumder N, Sharma I, Kaur I, Sundarrajan S, Venugopal JR, Vijayaraghavan P, Singh N, Ramakrishna S, Ghosh S, M Tripathi D, Kaur S. Liver Extracellular Matrix-Based Nanofiber Scaffolds for the Culture of Primary Hepatocytes and Drug Screening.ACS Biomater Sci Eng. 2023 Nov 13;9(11):6357-6368 
• 7. Juneja P, Ruhina Rahman SN, Jakhar D, Mourya AK, Tripathi DM, Kaur I, Tiwari V, Rohilla S, Gupta A, Rawal P, Baweja S, Rastogi A, Naidu VGM, Sarin SK, Banerjee S, Kaur S.JRecombinant VEGF-C (Cys156Ser) improves mesenteric lymphatic drainage and gut immune surveillance in experimental cirrhosis. JHEP Rep. 2023 Jun 17;5(10):100816. 
• 8. Juneja P, Sharma A, Shasthry SM, Kumar G, Tripathi DM, Rajan V, Rastogi A, Sarin SK, Kaur S. Podoplanin-positive dilated lymphatic vessels in duodenum associates with three-month mortality in patients with cirrhosis.Front Physiol. 2023 May 25;14:1045983 
• 9. Baweja S, Kumari A, Negi P, Tomar A, Tripathi DM, Mourya AK, Rastogi A, Subudhi PD, Thangariyal S, Kumar G, Kumar J, Reddy GS, Sood AK, Vashistha C, Sarohi V, Bihari C, Maiwall R, Sarin SK. Hepatopulmonary syndrome is associated with low sphingosine-1-phosphate levels and can be ameliorated by the functional agonist fingolimod. J Hepatol. 2023 Jul;79(1):167-180. 
• 10. Kaur I, Vasudevan A, Rawal P, Tripathi DM, Ramakrishna S, Kaur S, Sarin SK. Primary Hepatocyte Isolation and Cultures: Technical Aspects, Challenges and Advancements.Bioengineering (Basel). 2023 Jan 18;10(2):131 
• 11. Vasudevan A, Tripathi DM, Sundarrajan S, Venugopal JR, Ramakrishna S, Kaur S. Biomimetics Evolution of Electrospinning in Liver Tissue Engineering. 2022 Sep 30;7(4):149. 
• 12. Biswas S, Yadav N, Juneja P, Mourya AK, Kaur S, Tripathi DM, Chauhan VS. Conformationally Restricted Dipeptide-Based Nanoparticles for Delivery of siRNA in Experimental Liver Cirrhosis.ACS Omega. 2022 Oct 4;7(41):36811-36824. 
• 13. Puppala ER, Yalamarthi SS, Aochenlar SL, Prasad N, Syamprasad NP, Singh M, Nanjappan SK, Ravichandiran V, Tripathi DM, Gangasani JK, Naidu VGM. Mesua assamica (King&Prain) kosterm. Bark ethanolic extract attenuates chronic restraint stress aggravated DSS-induced ulcerative colitis in mice via inhibition of NF-κB/STAT3 and activation of HO-1/Nrf2/SIRT1 signaling pathways. J Ethnopharmacol. 2023 Jan 30;301:115765 
• 14. Puppala ER, Aochenlar SL, Shantanu PA, Ahmed S, Jannu AK, Jala A, Yalamarthi SS, Borkar RM, Tripathi DM, Naidu VGM. Perillyl alcohol attenuates chronic restraint stress aggravated dextran sulfate sodium-induced ulcerative colitis by modulating TLR4/NF-κB and JAK2/STAT3 signaling pathways. Phytomedicine. 2022 Nov; 
• 15. Biswas S, Vasudevan A, Yadav N, Yadav S, Rawal P, Kaur I, Tripathi DM, Kaur S, Chauhan VS. Chemically Modified Dipeptide Based Hydrogel Supports Three-Dimensional Growth and Functions of Primary Hepatocytes. ACS Appl Bio Mater. 2022 
• 16. Rawal P, Tripathi DM, Nain V, Kaur S. VEGF-mediated tumour growth and EMT in 2D and 3D cell culture models of hepatocellular carcinoma. Oncol Lett. 2022 Jul
• 17. Juneja P, Tripathi DM, Kaur S Revisiting the gut-liver axis: gut lymphatic system in liver cirrhosis and portal hypertension..Am J Physiol Gastrointest Liver Physiol. May, 2022 
• 18. Bihari C, Baweja S, Shasthry SM, Lal D, Negi P, Thangariyal S, Tripathi DM, Sarin SK. CEACAM-1 Induced CSF3-receptor Downregulation in Bone Marrow Associated With Refractory Neutropenia in Advanced Cirrhosis. Journal of Clinical and Translational Hepatology, Accepted Feb 2022 
• 19. De Shreemoyee, Joshi Akshay, Tripathi M Dinesh, Kaur Savneet, Singh Neetu. Alginate based 3D micro-scaffolds mimicking tumor architecture as in vitro cell culture platform. Materials Science and Engineering July 2021 . (IF: 7.3)
• 20. Nidhi Nautiyal; Deepanshu Maheshwari; Dinesh Mani Tripathi; Dhananjay Kumar; Rekha Kumari; Suchi Gupta; Sachin Sharma; Sujata Mohanty; Anupama Parasar; Chhagan Bihari; Subhrajit Biswas; Archana Rastogi; Rakhi Maiwall; Anupam Kumar; Shiv Kumar Sarin "Establishment of a Murine Model of Acute-on-Chronic Liver Failure with Multi-organ Dysfunction" Hepatology International (IF 6.04)
• 21. Impreet Kaur, Sumati Rohilla, Ashwini Vasudevan, Pinky Juneja, Chandan Kumar Verma,Preety Rawal, Aarushi Sharma, Sadam Hussain Bhat, Sundarrajan Subramanian, Chaggan Bihari, Sourabh Ghosh, Seeram Ramakrishna, Dinesh M Tripathi*, Savneet Kaur* Liver ECM-based Scaffolds Support Hepatocyte Proliferation and Differentiation in Injured Liver. Molecules 2021, (IF: 4.4) 
• 22. Sharma Aarushi, Rawal, Preety, Tripathi Dinesh Mani, Alodiya Dashrath, Sarin Shiv Kumar, Kaur Savneet, Ghosh Sourabh et.al "Upgrading Hepatic Differentiation and Functions on 3D-Printed Silk-Decellularized Liver Hybrid Scaffolds" ACS Biomaterials Science & Engineering July 2021. (IF: 4.7) 
• 23. Tripathi, D.M.; Rohilla, S.; Kaur, I.; Siddiqui, H.; Rawal, P.; Juneja, P.; Kumar, V.; Kumari, A.; Naidu, V.; Ramakrishna, S.; et al. Immunonano-lipocarrier-Mediated Liver Sinusoidal Endothelial Cell-Specific RUNX1 Inhibition Impedes Immune Cell Infiltration and Hepatic Inflammation in Murine Model of NASH. Int. J. Mol. Sci. 2021. 
• 24. Savneet Kaur, Sadam Hussain, Kailash Kolhe, Guresh Kumar, Dinesh M Tripathi, Arvind Tomar , Pratibha Kale, Ashad Narayanan, Chaggan Bihari , Meenu Bajpai, Rakhi Maiwall, Ekta Gupta, Shiv K Sarin. "Elevated Plasma ICAM1 Levels Predict 28-day Mortality in Cirrhotic Patients with Covid-19 or Bacterial Sepsis", JHEP Reports. 
• 25. Taruna Madan, Barnali Biswas, Praveen M. Varghese, RambhadurSubedi, Hrishikesh Pandit, Susan Idicula-Thomas, Indra Kundu, SheetalnathRooge, Reshu Agarwal, Dinesh M. Tripathi, Savneet Kaur, Ekta Gupta, Sanjeev K. Gupta, Uday Kishore.A recombinant fragment of human surfactant protein D binds Spike protein and inhibits infectivity and replication of SARS-CoV-2 in clinical samples. American Journal of Respiratory Cell and Molecular Biology. 2021. 
• 26. Impreet Kaur; Preety Rawal; Dinesh M Tripathi; Ashwini Vasudevan, Savneet Kaur. Non-matrigel Scaffolds for Organoid Cultures. Cancer Letters 2021 (IF: 7.36) 
• 27. Preety Rawal, Savneet Kaur, Dinesh M. Tripathi, Jayarama Reddy Venugopal, Seeram Ramakrishna. Prospects for 3D bioprinting of organoids, Bio-Designing and manufacturing, 2021 (IF: 4.09) 
• 28. Savneet Kaur, Dinesh M. Tripathi, Jayarama Reddy Venugopal, Seeram Ramakrishna. Advances in biomaterials for hepatic tissue engineering. Current Opinion in Biomedical Engineering, 13, 2020. (IF: 3.37) 
• 29. Dinesh Mani Tripathi, Mohsin Hassan, Hamda Sidiqqui, Impreet Kaur, Preety Rawal, Chaggan Bihari, Savneet Kaur and Shiv K Sarin. Cirrhotic Endothelial Progenitor Cells Enhance Liver Angiogenesis and Fibrosis and Aggravate Portal Hypertension in Bile Duct-Ligated Cirrhotic Rats. Front Physiol. 2020. (IF: 3.37) 
• 30. Savneet Kaur, Dinesh M Tripathi, Angeera Yadav. The Enigma of Endothelium in COVID-19. Front Physiol. 2020. (IF: 3.37) 
• 31. Savneet Kaur, Dinesh M Tripathi, Sourabh Ghosh. Three-dimensional bioprinted hepatorganoids in liver failure. GUT. 10.1136/gutjnl-2020-322317. (IF: 19.81) 
• 32. Kailash Kolhe, Dinesh M Tripathi, Savneet Kaur Management of Portopulmonary hypertension: What is more important: PAH severity or liver disease severity? J Hepatology, 2020. (IF: 20.51) 
• 33. Kaur S, Rawal P, Siddiqui H, Rohilla S, Sharma S, Tripathi DM, Baweja S, Hassan M, Vlaic S, Guthke R, Thomas M, Dayoub R, Bihari C, Sarin SK, Weiss TS. Increased Expression of RUNX1 in Liver Correlates with NASH Activity Score in Patients with Non-Alcoholic Steatohepatitis (NASH). Cells. 2019 Oct 18;8(10) (IF: 5.656)
• 34. Preety Rawal, Hamda Siddiqui, Mohsin Hassan, Manish Chaudhary, Dinesh M Tripathi, Vikrant Nain, Nirupma Trehanpati, Savneet Kaur. Endothelial cell-derived TGF-β Promotes Epithelial-Mesenchymal Transition via CD133 in HBx-infected Hepatoma cells, Front Oncol. 2019 (IF: 4.137)
• 35. Dinesh Mani Tripathi, Vilaseca M, Lafoz E, Garcia-Caldero H, Haute GV, Fernández Iglesias A, de Oliveira JR, Garcia-Pagan JC, Bosch J, Gracia-Sancho J, Simvastatin Prevents Progression of Acute on Chronic Liver Failure in Rats With Cirrhosis and Portal Hypertension, Gastroenterology (2018) (IF: 20.77)
• 36. Cerini F, Vilaseca M, Lafoz E, García-Irigoyen O, García-Calderó H, Tripathi DM, Avila M, Reverter JC, Bosch J, Gracia-Sancho J, García-Pagán JC Enoxaparin reduces hepatic vascular resistance and portal pressure in cirrhotic rats. J Hepatol. 2017 (IF :20.51)
• 37. Dinesh Mani Tripathi; Marina Vilaseca; Erica Lafoz; Juan Carlos Garcia Pagan. Role of oxidative stress in portal hypertension in cirrhosis. Gastrointestinal Tissue: Oxidative Stress and Dietary Antioxidants¨. ISBN 9780128053775, Elsevier, 2017
• 38. Dinesh Mani Tripathi, Eva, Jorge Gracia-Sancho, Hector Garcia-Caldero, Jaume Bosch, S.K. sarin Joan-Carles Garcia-Pagan Metformin, reduces hepatic resistance and portal pressure In CCl4 and BDL Cirrhotic rats. American Journal of Physiology Gastrointestinal and Liver Physiology 2015 (IF 3.8)
• 39. Eugenio Rosado, Aina Rodriguez-Vilarrupla, Jorge Gracia-Sancho, Dinesh Tripathi, Hector Garcia- Caldero, Jaume Bosch, Joan-Carles Garcia-Pagan “Terutroban, a TP-Receptor antagonist, reduces Portal Pressure in Cirrhotic rats” Hepatology.2013 (IF 14.67)
• 40. Sujoy Bose, Dinesh M Tripathi, Sukriti, Puja Sakhuja, Kazim S.N, Shiv K Sarin “Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: Association with hepatitis B related advanced liver disease and cancer in north Indian population” Gene. 2013 May (IF 2.13)
• 41. Savneet kaur, Dinesh M Tripathi, Ketki Dongre, Puja sakhuja, Ashok Mukhopadhya, Shiv Kumar Sarin.“Increased number and function of endothelial progenitor cells stimulate angiogenesis by resident liver sinusoidalendothelial cells (SECs) in cirrhosis through paracrine factors”. J Hepatol. 2012 (IF 20.51)
• 42. Nirupama Trehanpati, Shikha Shrivastav, Bhavana Shivakumar, Ritu Khosla, Suvercha Bhardwaj, , Sukriti, Sujoy Bose, Dinesh Mani Tripathi, Trinath Das, Puja Sakhuja, Archana Rastogi, Chagan Bhihari, Shivender Singh, Subhash Gupta, Shyam Kottilil, Shiv Kumar Sarin " Analysis of Notch and TGF-β Signaling Expression in Different Stages of Disease Progression During Hepatitis B Virus Infection" Clinical Translational Gastroenterology. 2012 (IF 3.47)