Pre-Clinical Animal Models of Liver Diseases
ILBS is a pioneer center for development of well-characterized pre-clinical animal models of liver disease and regeneration across the country.
- Liver Fibrosis, Cirrhosis and Portal Hypertension ( Toxin-induced, Carbon tetra chloride; CCl4 and Thioacetamide-TAA)
- Cholestatic liver disease Model (Surgically induced, ligation of Common Bile duct )
- Non-alcoholic fatty liver disease (NAFLD) (High fat diet & Methionone-Choline Deficient Diet)
- Alcoholic liver disease (ALD) (Alcohol intoxication Model)
- Acute on Chronic Liver Failure (ACLF) (Endotoxin-induced Sepsis Liver Failure)
- Animal models of liver regeneration (Surgically induced partial hepactectomy)
- Non-cirrhotic portal hypertension (Endotoxin-induced)
- Animal Model of Pre-hepatic portal hypertension (Surgically induced -Partial Portal Vein ligation, PPVL)
- Hepatocellular Carcinoma (Carcinogen Diethyl nitrosamine (DEN)-induced)
