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Pre-Clinical Animal Models Of Liver Diseases

Pre-Clinical Animal Models of Liver Diseases

ILBS is a pioneer center for development of well-characterized pre-clinical animal models of liver disease and regeneration across the country.

  • Liver Fibrosis, Cirrhosis and Portal Hypertension ( Toxin-induced, Carbon tetra chloride; CCl4 and Thioacetamide-TAA)
  • Cholestatic liver disease Model (Surgically induced, ligation of Common Bile duct )
  • Non-alcoholic fatty liver disease (NAFLD) (High fat diet & Methionone-Choline Deficient Diet)
  • Alcoholic liver disease (ALD) (Alcohol intoxication Model)
  • Acute on Chronic Liver Failure (ACLF) (Endotoxin-induced Sepsis Liver Failure)
  • Animal models of liver regeneration (Surgically induced partial hepactectomy)
  • Non-cirrhotic portal hypertension (Endotoxin-induced)
  • Animal Model of Pre-hepatic portal hypertension (Surgically induced -Partial Portal Vein ligation, PPVL)
  • Hepatocellular Carcinoma (Carcinogen Diethyl nitrosamine (DEN)-induced)

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